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P45907

Piperazine

99%, solid, suitable for synthesis, ReagentPlus®

Synonym(s):

1,4-Diazacyclohexane, Diethylenediamine

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About This Item

Empirical Formula (Hill Notation):
C4H10N2
CAS Number:
Molecular Weight:
86.14
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
39160301
UNSPSC Code:
12352100
EC Number:
203-808-3
MDL number:
Beilstein/REAXYS Number:
102555
Assay:
99%
Bp:
145-146 °C (lit.)
Vapor pressure:
0.8 mmHg ( 20 °C)
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Product Name

Piperazine, ReagentPlus®, 99%

vapor pressure

0.8 mmHg ( 20 °C)

Quality Level

product line

ReagentPlus®

assay

99%

form

solid

expl. lim.

14 %

dilution

(for general lab use)

impurities

<1% water

pH

10.8-11.8 (100 g/L)

bp

145-146 °C (lit.)

mp

109-112 °C (lit.)

solubility

H2O: 0.9 g/L at 20 °C

SMILES string

C1CNCCN1

InChI

1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2

InChI key

GLUUGHFHXGJENI-UHFFFAOYSA-N

General description

Piperazine (PZ) is an amine solvent. The ability of aqueous PZ to absorb carbon dioxide (CO2) has been assessed. It is reported to cause paralysis in Ascaris worms. The analysis of the crystal structure of PZ at 150K shows the presence of layered structure with NH...N hydrogen-bonded chains.[1]

Application

Intermediate for a wide range of pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.
Piperazine may be used in the preparation of N-(hetero)arylpiperazines.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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1 of 1

This Item
80621SMB000971541601
Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

-

assay

99%

assay

≥99.0% (T)

assay

≥95% (LC/MS-ELSD)

assay

-

solubility

H2O: 0.9 g/L at 20 °C

solubility

H2O: 0.1 M at 20 °C, clear, colorless

solubility

-

solubility

-

form

solid

form

solid

form

solid

form

-

pH

10.8-11.8 (100 g/L)

pH

11.0-12.5 (25 °C, 0.1 M in H2O)

pH

-

pH

-

mp

109-112 °C (lit.)

mp

109-112 °C (lit.)

mp

-

mp

109-112 °C (lit.)


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signalword

Danger

Hazard Classifications

Eye Dam. 1 - Flam. Sol. 1 - Repr. 2 - Resp. Sens. 1B - Skin Corr. 1B - Skin Sens. 1B

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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Carbon dioxide capture with concentrated, aqueous piperazine.
Freeman SA, et al.
International Journal of Greenhouse Gas Control, 4(2), 119-124 (2010)
Absorption of carbon dioxide into aqueous piperazine: reaction kinetics, mass transfer and solubility.
Bishnoi S and Rochelle GT.
Chemical Engineering Science, 55(22), 5531-5543 (2000)
Synthesis of N-arylpiperazines from aryl halides and piperazine under a palladium tri-tert-butylphosphine catalyst.
Nishiyama M, et al.
Tetrahedron Letters, 39(7), 617-620 (1998)



Global Trade Item Number

SKUGTIN
P45907-100G04061835321377
P45907-1KG04061834374862
P45907-12KG04061833694398
P45907-500G04061834374886
P45907-5G04061834374893
P45907-2.5KG04061834374879

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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