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MilliporeSigma

P5413

Poly(ethylene glycol)

greener alternative

Molecular Biology, average mol wt 8,000

Synonym(s):

Poly (ethylene oxide), Polyethylene glycol, PEG

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500 G

$101.00

1 KG

$131.00

2 KG

$256.00

$101.00


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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
NACRES:
NA.31
PubChem Substance ID:
UNSPSC Code:
12352104
MDL number:

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InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

SMILES string

C(CO)O

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

grade

Molecular Biology

form

powder

mol wt

average mol wt 8,000

Quality Level

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

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solubility

water: soluble (approximately 630 mg/ml, 20 °C)

density

1.0845 g/mL at 70 °C, 1.0689 g/mL at 90 °C

foreign activity

DNase, RNase and NICKase, none detected

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1 of 4

This Item
P32658126881260
form

powder

form

liquid

form

powder

form

flakes

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

300

mol wt

average mol wt 8,000

mol wt

average mol wt 400

mol wt

Mr 7000-9000

mol wt

Mn 5,000-7,000, average Mn 6,000

density

1.0845 g/mL at 70 °C, 1.0689 g/mL at 90 °C

density

1.1254 g/cm3 at 20 °C, 1.0930 g/cm3 at 60 °C

density

1.0845 g/mL at 70 °C, 1.0689 g/mL at 90 °C

density

-

grade

for molecular biology

grade

-

grade

for molecular biology

grade

-

solubility

water: soluble (approximately 630 mg/ml, 20 °C)

solubility

water: 100 mg/mL

solubility

H2O: 50 mg/mL at 20 °C, clear, colorless

solubility

-

Application

Poly(ethylene glycol) has been used:
  • in protoplast suspension[1]
  • to prevent phase separation in emulsion[2]
  • in phage tail-like particles precipitation[3]
  • for purifying and intensifying products of polymerase chain reaction[4]

General description

Polyethylene glycol (PEG) is a polymer of ethylene oxide and water, obtained upon condensation.[5] PEGs are susceptible to oxidative degradation in the presence of air. Minimizing the exposure of PEG to elevated temperatures and/or exposure to oxygen or addition of an antioxidant can limit the amount of degradation. PEGs do not hydrolyze or deteriorate upon storage. PEGs do not support the growth of molds.[6]
Polyethylene glycol (PEG) is used in detergents, emulsifying agents, soaps, metal costing process, pharmaceutical preparations and cosmetics.[5] PEG is commonly used as a lubricant. It′s application is also observed in chromatographic stationary phases.[6] PEG prevents crystal formation in emulsions.[2]
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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John M Murray
Journal of microscopy, 267(2), 193-213 (2017-03-23)
The ability to replace genes coding for cellular proteins with DNA that codes for fluorescent protein-tagged versions opens the way to counting the number of molecules of each protein component of macromolecular assemblies in vivo by measuring fluorescence microscopically. Converting
Associations between HLA class I alleles and escape mutations in the hepatitis B virus core gene in New Zealand-resident Tongans
Abbott William GH, et al.
Journal of Virology, 84(1), 621-629 (2010)
Genes for the biosynthesis of the fungal polyketides hypothemycin from Hypomyces subiculosus and radicicol from Pochonia chlamydosporia
Reeves CD
Applied and Environmental Microbiology, 74(16), 5121-5129 (2008)
Retinol encapsulated into amorphous Ca2+ polyphosphate nanospheres acts synergistically in MC3T3-E1 cells
Muller Werner EG, et al.
European Journal of Pharmaceutics and Biopharmaceutics, 93, 214-223 (2015)
Induction and Purification of C. difficile Phage Tail-Like Particles
Clostridium difficile, 167-175 (2016)

Related Content

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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