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P8574

Sigma-Aldrich

Sodium pyruvate

BioXtra, ≥99%

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Synonym(s):
α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt
Linear Formula:
CH3COCOONa
CAS Number:
Molecular Weight:
110.04
Beilstein/REAXYS Number:
3568341
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.71

product line

BioXtra

Quality Level

assay

≥99%

form

powder

impurities

≤0.005% Phosphorus (P)
≤0.1% Insoluble matter

mp

>300 °C (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.001%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

storage temp.

2-8°C

SMILES string

[Na+].CC(=O)C([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1

InChI key

DAEPDZWVDSPTHF-UHFFFAOYSA-M

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1 of 4

This Item
P4562S8636P3662
vibrant-m

P8574

Sodium pyruvate

Premium Grade
vibrant-m

P4562

Sodium pyruvate

-
vibrant-m

S8636

Sodium pyruvate solution

-
vibrant-m

P3662

Sodium pyruvate

-
solubility

H2O: 1 M, clear, colorless

solubility

H2O: 100 mg/mL

solubility

-

solubility

H2O: 100 mg/mL

assay

≥99%

assay

≥99%

assay

-

assay

≥99%

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

-

mp

>300 °C (lit.)

form

powder

form

powder

form

solution

form

powder

Application

Sodium pyruvate has been used as a component:
  • of cutting solution for rat brain tissue slice preparation
  • of M-199 medium for the maturation of oocytes
  • of Krebs-Henseleit buffer for plasma incubation

Biochem/physiol Actions

Sodium pyruvate based therapeutic regimen is effective for treating mitochondrial diseases. It decreases tissue damage associated with the pathophysiology of brain damage, haemorrhagic shock and ischemia-reperfusion injury models.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1B

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Biomarkers and clinical rating scales for sodium pyruvate therapy in patients with mitochondrial disease
Koga Y, et al.
Mitochondrion (2019)
Transcriptome and proteome analysis of soleus muscle of hormone-sensitive lipase-null mice
Hansson O, et al.
Journal of Lipid Research, 46(12), 2614-2623 (2005)
Imaging calcium concentration dynamics in small neuronal compartments
Yasuda R, et al.
Science's STKE : Signal Transduction Knowledge Environment, 2004(219) (2004)
Embryonic development after follicle culture is influenced by follicle-stimulating hormone isoelectric point range
Vitt UA, et al.
Biology of Reproduction, 65(5) (2001)
Addition of sodium pyruvate to stored red blood cells attenuates liver injury in a murine transfusion model
Xia S, et al.
Mediators of Inflammation, 2016 (2016)

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