PHL80379

Cardamomin

phyproof® Reference Substance

Synonym(s):
(8CI); Alpinetin chalcone, (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one, (E)-2′,4′-Dihydroxy-6′-methoxy-chalcone, Cardamonin
Empirical Formula (Hill Notation):
C16H14O4
CAS Number:
Molecular Weight:
270.28
MDL number:

grade

primary reference standard

product line

phyproof® Reference Substance

assay

≥98.0% (HPLC)

manufacturer/tradename

PhytoLab

format

neat

storage temp.

2-8°C

SMILES string

O=C(/C=C/C1=CC=CC=C1)C2=C(O)C=C(O)C=C2OC

InChI

1S/C16H14O4/c1-20-15-10-12(17)9-14(19)16(15)13(18)8-7-11-5-3-2-4-6-11/h2-10,17,19H,1H3/b8-7+

InChI key

NYSZJNUIVUBQMM-BQYQJAHWSA-N

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General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Cardamonin is a calchone from Aplinia species (zingiberaceous plant species). Cardamonin inhibits pigmentation in melanocytes through suppression of Wnt/b-catenin signaling pathway. Cardamonin suppressed Wnt/b-catenin signaling by a mechanism involving proteasome-mediated degradation of b-catenin (GSK-3b-independent pathway). Research has shown that Cardamonin possesses anti-inflammatory activity via suppression of NF-kB nuclear translocation and Ik-Ba phosphorylation.

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

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