PHR1022

Butylparaben

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): 4-Hydroxybenzoic acid butyl ester
• Empirical Formula (Hill Notation): C₁₁H₁₄O₃
• CAS Number: 94-26-8
• Molecular Weight: 194.23
• NACRES: NA.24
• UNSPSC Code: 41116107
• EC Number: 202-318-7
• MDL number: MFCD00016478
• Beilstein/REAXYS Number: 1103741

Properties

• Quality Segment: 300
• grade: certified reference material, pharmaceutical secondary standard
• agency: traceable to Ph. Eur. B1217000, traceable to USP 1084000
• API family: parabens
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: O(CCCC)C(=O)c1ccc(cc1)O
• InChI: 1S/C11H14O3/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7,12H,2-3,8H2,1H3
• InChI key: QFOHBWFCKVYLES-UHFFFAOYSA-N

Description

General description

Butylparaben is a compound, which belongs to the class of parabens.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)

Application

Butylparaben may be used as a reference standard for the determination of the analyte in cosmetics, food samples[1] and human breast cancerous tissue by chromatography techniques.

Butylparaben may be used as an internal standard in the analysis of aspirin and warfarin in pharmaceutical formulations using reversed-phase high performance liquid chromatography (RP-HPLC).

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAB7759 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• pictograms: GHS05
• signalword: Danger
• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• hcodes: H315,H318,EUH380
• pcodes: P201 - P202 - P263 - P280 - P305 + P351 + P338 - P308 + P313 - P405 - P501
• Hazard Classifications: ED HH 1 - Eye Dam. 1 - Skin Irrit. 2