PHR1048

4-Hydroxybenzoic acid

Pharmaceutical Secondary Standard; Certified Reference Material

• Linear Formula: HOC₆H₄CO₂H
• CAS Number: 99-96-7
• Molecular Weight: 138.12
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329823078
• EC Number: 202-804-9
• Beilstein/REAXYS Number: 970950
• MDL number: MFCD00002547
• eCl@ss: 25140904

Properties

• Quality Segment: 300
• grade: certified reference material, pharmaceutical secondary standard
• agency: traceable to USP 1609013
• API family: 4-hydroxybenzoic acid
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• mp: 213-217 °C (lit.)
• application(s): cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care; pharmaceutical (small molecule); pharmaceutical
• format: neat
• storage temp.: 2-30°C
• SMILES string: OC(=O)c1ccc(O)cc1
• InChI: 1S/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10)
• InChI key: FJKROLUGYXJWQN-UHFFFAOYSA-N

Description

General description

This compound can be found as a component in plants of the genus: aloe, carum, cinnamomum, lycium, thymus

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. 4-Hydroxybenzoic acid belongs to the class of aromatic acids, which may be used as a preservative in cosmetics, pharmaceuticals and as a synthetic flavoring agent in food products.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAB2176 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Codes: H318,H335
• Precautionary Statements: P261 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338 - P403 + P233
• Hazard Classifications: Eye Dam. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable