Residual Solvents Mixture - Class IIB

Pharmaceutical Secondary Standard; Certified Reference Material


Quality Level


certified reference material
pharmaceutical secondary standard


current certificate can be downloaded


suitable for 467 per USP

Featured Industry

Pharmaceutical (small molecule)


multi-component solution

pharmacopeia traceability

traceable to USP 1601292

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Sigma-Aldrich offers Fluka brand Certified Reference Materials (CRMs) for the analysis of Residual Solvents. These CRMs are Secondary Pharmaceutical Reference Standards and are traceable and qualified against the corresponding Pharmacopeial standards. A comprehensive Certificate of Analysis offers details of the methodology and results of the qualification.


These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.


To see an example of a Certificate of Analysis for this material enter LRAB3700 in the slot below. This is an example certificate only and may not be the lot that you receive.



    Chloroform 60 μg/mL
    1,2-Dimethoxyethane 100 μg/mL
    Hexane 290 μg/mL
    3-Methyl-2-pentanone 50 μg/mL
    Nitromethane 50 μg/mL
    Pyridine 200 μg/mL
    Tetralin 100 μg/mL
    Trichloroethylene 80 μg/mL
    See All (8)


10 - Combustible liquids

WGK Germany


Flash Point(F)

188.6 °F

Flash Point(C)

87 °C

Certificate of Analysis

Certificate of Origin

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