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PHR1172

Supelco

L-Valine

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
L-Valine, (S)-α-Aminoisovaleric acid, L-2-Amino-3-methylbutanoic acid
Linear Formula:
(CH3)2CHCH(NH2)CO2H
CAS Number:
Molecular Weight:
117.15
Beilstein:
1721136
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to USP 1708503

API family

valine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

295-300 °C (subl.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CC(C)[C@H](N)C(O)=O

InChI

1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1

InChI key

KZSNJWFQEVHDMF-BYPYZUCNSA-N

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This Item
50848V4638V0500
L-Valine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1172

L-Valine

-
L-Valine certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

50848

L-Valine

-
L-Valine

SAFC

V4638

L-Valine

-
L-Valine reagent grade, ≥98% (HPLC)

Sigma-Aldrich

V0500

L-Valine

Essential Grade
technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

thin layer chromatography (TLC): suitable

application(s)

pharmaceutical (small molecule)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

application(s)

pharmaceutical (small molecule)

application(s)

-

format

neat

format

neat

format

-

format

-

storage temp.

2-30°C

storage temp.

20-25°C

storage temp.

2-30°C

storage temp.

-

Quality Level

300

Quality Level

300

Quality Level

400

Quality Level

200

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Valine is an essential amino acid, involved in the biosynthesis of glutamine and alanine. Valine being a branched-chain amino acid (BCAA), maintains a balance among the BCAAs. L-Valine serves as an energy fuel.

Application

L-Valine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high-performance liquid chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Values of analytes vary lot to lot.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7145 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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HPLC-fluorescence determination of amino acids in pharmaceuticals after pre-column derivatization with phanquinone
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Journal of Pharmaceutical and Biomedical Analysis, 35(2), 339-348 (2004)
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