MilliporeSigma
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PHR1207

Supelco

Methyl Ethyl Ketone

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
2-Butanone, Ethyl methyl ketone, MEK, Methyl ethyl ketone
Linear Formula:
C2H5COCH3
CAS Number:
Molecular Weight:
72.11
Beilstein:
741880
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to USP 1430101

vapor density

2.49 (vs air)

vapor pressure

71 mmHg ( 20 °C)

CofA

current certificate can be downloaded

autoignition temp.

960 °F

expl. lim.

10.1 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.379 (lit.)

bp

80 °C (lit.)

mp

−87 °C (lit.)

density

0.805 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CC(CC)=O

InChI

1S/C4H8O/c1-3-4(2)5/h3H2,1-2H3

Inchi Key

ZWEHNKRNPOVVGH-UHFFFAOYSA-N

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This Item
1430101RTC0000861.09708
Methyl Ethyl Ketone Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1207

Methyl Ethyl Ketone

Methyl ethyl ketone United States Pharmacopeia (USP) Reference Standard

USP

1430101

Methyl ethyl ketone

Methyl Ethyl Ketone Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

RTC000086

Methyl Ethyl Ketone

Ethyl methyl ketone for analysis EMSURE® ACS,Reag. Ph Eur

Supelco

1.09708

Ethyl methyl ketone

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

ACS reagent

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

format

neat

format

neat

format

-

format

-

storage temp.

2-30°C

storage temp.

-

storage temp.

2-30°C

storage temp.

2-30°C

Quality Level

300

Quality Level

-

Quality Level

-

Quality Level

300

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. 2-Butanone (Methyl ethyl ketone, MEK), an aliphatic ketone, is considered as an aprotic and protophilic solvent. Its ability as an anticonvulsive agent in lithium-pilocarpine-induced status epilepticus in rats is reported.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC0146 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

30.2 °F - closed cup

Flash Point(C)

-1 °C - closed cup


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