PHR1213

Supelco

Benzyl benzoate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
Benzoic acid benzyl ester
Linear Formula:
C6H5COOCH2C6H5
CAS Number:
Molecular Weight:
212.24
Beilstein/REAXYS Number:
2049280
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

certified reference material
pharmaceutical secondary standard

vapor pressure

1 mmHg ( 125 °C)

form

neat

CofA

current certificate can be downloaded

autoignition temp.

896 °F

application(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.568 (lit.)

bp

323-324 °C (lit.)

mp

17-20 °C (lit.)

density

1.118 g/mL at 20 °C (lit.)

Featured Industry

Pharmaceutical (small molecule)

format

neat

pharmacopeia traceability

traceable to USP 1062008

SMILES string

O=C(OCc1ccccc1)c2ccccc2

InChI

1S/C14H12O2/c15-14(13-9-5-2-6-10-13)16-11-12-7-3-1-4-8-12/h1-10H,11H2

InChI key

SESFRYSPDFLNCH-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Benzyl benzoate is an acaricidal drug effective against scabies mites belonging to the genus Dermatophagoides.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Benzyl benzoate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high-performance liquid chromatography method.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC1688 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

hazcat

Acute Tox. 4 Oral - Aquatic Chronic 2

storage_class_code

10 - Combustible liquids

WGK Germany

WGK 2

Flash Point(F)

298.4 °F - closed cup

Flash Point(C)

148 °C - closed cup

Certificate of Analysis

Certificate of Origin

Benzyl benzoate moist powder: investigation of acarical activity in cultures and reduction of dust mite allergens in carpets.
Hayden ML, et al.
The Journal of Allergy and Clinical Immunology, 89(2), 536-545 (1992)
Separation and simultaneous high-performance liquid chromatographic determination of benzocaine and benzyl benzoate in a pharmaceutical preparation.
Gigante B, et al.
Journal of Chromatography A, 549(2), 217-220 (1991)
Glen H MacDonald et al.
Hearing research, 243(1-2), 1-10 (2008-06-25)
The complex anatomy of the mammalian cochlea is most readily understood by representation in three-dimensions. However, the cochlea is often sectioned to minimize the effects of its anatomic complexity and optical properties on image acquisition by light microscopy. We have...
Jing-Liang Li et al.
The journal of physical chemistry. B, 113(15), 5011-5015 (2009-03-25)
The formation of most organogels requires the compatibility of both the gelator and solvent. It is very desirable if the rheological properties of a gel can be manipulated to achieve the desired performance. In this paper, a novel organogel was...
Ben Spitzer-Rimon et al.
The Plant cell, 22(6), 1961-1976 (2010-06-15)
Floral scent, which is determined by a complex mixture of low molecular weight volatile molecules, plays a major role in the plant's life cycle. Phenylpropanoid volatiles are the main determinants of floral scent in petunia (Petunia hybrida). A screen using...

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