Benzyl benzoate

Pharmaceutical Secondary Standard; Certified Reference Material

Benzoic acid benzyl ester
Linear Formula:
CAS Number:
Molecular Weight:
Beilstein/REAXYS Number:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


certified reference material
pharmaceutical secondary standard

vapor pressure

1 mmHg ( 125 °C)




current certificate can be downloaded

autoignition temp.

896 °F


HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.568 (lit.)


323-324 °C (lit.)


17-20 °C (lit.)


1.118 g/mL at 20 °C (lit.)

Featured Industry

Pharmaceutical (small molecule)



pharmacopeia traceability

traceable to USP 1062008

SMILES string




InChI key


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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Benzyl benzoate is an acaricidal drug effective against scabies mites belonging to the genus Dermatophagoides.


These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Benzyl benzoate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high-performance liquid chromatography method.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.


To see an example of a Certificate of Analysis for this material enter LRAC1688 in the slot below. This is an example certificate only and may not be the lot that you receive.


Exclamation markEnvironment

Signal Word


Hazard Statements


UN 3082 9 / PGIII

WGK Germany


Flash Point(F)

298.4 °F - closed cup

Flash Point(C)

148 °C - closed cup

Certificate of Analysis

Certificate of Origin

Separation and simultaneous high-performance liquid chromatographic determination of benzocaine and benzyl benzoate in a pharmaceutical preparation.
Gigante B, et al.
Journal of Chromatography A, 549(2), 217-220 (1991)
Benzyl benzoate moist powder: investigation of acarical activity in cultures and reduction of dust mite allergens in carpets.
Hayden ML, et al.
The Journal of Allergy and Clinical Immunology, 89(2), 536-545 (1992)
Catherine W McCollum et al.
Aquatic toxicology (Amsterdam, Netherlands), 152, 152-163 (2014-04-29)
Exposure to arsenic in its inorganic form, arsenite, causes adverse effects to many different organs and tissues. Here, we have investigated arsenite-induced adverse effects on vascular tissues in the model organism zebrafish, Danio rerio. Zebrafish embryos were exposed to arsenite...
Karina Caballero-Gallardo et al.
Journal of agricultural and food chemistry, 59(5), 1690-1696 (2011-02-05)
A tool for integrated pest management is the use of essential oils (EOs) and plant extracts. In this study, EOs from Tagetes lucida , Lepechinia betonicifolia , Lippia alba , Cananga odorata , and Rosmarinus officinalis , species grown in...
Mayumi Bowen et al.
Journal of pharmaceutical sciences, 101(12), 4433-4443 (2012-09-25)
Developing high-concentration monoclonal antibody (mAb) liquid formulations for subcutaneous (s.c.) administration is challenging because increased viscosity makes injection difficult. To overcome this obstacle, we investigated a nonaqueous powder suspension approach. Three IgG1 mAbs were spray dried and suspended at different...

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