PHR1326

Calcium carbonate

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Calcium carbonate
• Linear Formula: CaCO₃
• CAS Number: 471-34-1
• Molecular Weight: 100.09
• Beilstein: 8008338
• EC Number: 207-439-9
• MDL number: MFCD00010906
• PubChem Substance ID: 329823311
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to USP 1086403
• API family: calcium carbonate
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• density: 2.93 g/mL at 25 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: [Ca++].[O-]C([O-])=O
• InChI: 1S/CH2O3.Ca/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2
• InChI key: VTYYLEPIZMXCLO-UHFFFAOYSA-L

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Calcium carbonate is a material that is widely found in nature, and is commonly referred to as calcite. Calcium carbonate is used in such processes as the manufacture of paper, paints, glass, and ceramics, the compounding of polymers, environmental applications such as wastewater treatment, and as an extender in paints and coatings.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3446 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable