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MilliporeSigma

PHR1371

Benzalkonium Chloride 10% Solution

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Benzalkonium chloride solution, Alkylbenzyldimethylammonium chloride

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5 ML

$114.00

$114.00


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About This Item

CAS Number:
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:

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SMILES string

[Cl-].[N+](CCCCCCCCCC)(Cc1ccccc1)(C)C

InChI

1S/C19H34N.ClH/c1-4-5-6-7-8-9-10-14-17-20(2,3)18-19-15-12-11-13-16-19;/h11-13,15-16H,4-10,14,17-18H2,1-3H3;1H/q+1;/p-1

InChI key

TTZLKXKJIMOHHG-UHFFFAOYSA-M

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1051001

API family

benzalkonium chloride

CofA

current certificate can be downloaded

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

2-30°C

Quality Level

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1 of 4

This Item
Y00010601.371241.37123
application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

liquid formulation
ophthalmics
parenterals
pharmaceutical
semi-solid formulation

application(s)

liquid formulation
ophthalmics
parenterals
pharmaceutical
semi-solid formulation

format

single component solution

format

neat

format

-

format

-

Quality Level

300

Quality Level

-

Quality Level

500

Quality Level

500

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

-

grade

-

storage temp.

2-30°C

storage temp.

2-8°C

storage temp.

15-25°C

storage temp.

15-25°C

agency

traceable to USP 1051001

agency

-

agency

NF, Ph. Eur.

agency

JP, NF, Ph. Eur.

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC2017 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

CorrosionEnvironment

signalword

Danger

hcodes

Hazard Classifications

Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Questions

1–5 of 5 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. I understand that benzalkonium chloride consists of substances with methyl groups of 10, 12, 14, 16, and 18. Is the benzalkonium chloride solution enrolled above a mixture of these different benzalkonium chlorides? If so, what is the ratio?

    1 answer
    1. This product consists of the C10, C12, C14, C16, and C18 homologs of benzalkonium chloride, but the exact percentages of these homologs varies slightly from lot to lot. For the percentages of homologs present in a specific batch, please refer to the lot-specific Certificate of Analysis.

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  4. is a solution 10% w/w?

    1 answer
    1. This product is 10% (w/v). Please view the Sample Certificate of Analysis below for more information:
      https://www.sigmaaldrich.com/certificates/Graphics/COfAInfo/fluka/pdf/rtc/PHR1371_LRAD1895.pdf.

      Helpful?

  5. Can I get additional information regarding the Ratio Determination for C18? Is this standard appropriate for use in a pharmaceutical quality control laboratory? Ar the CoA results provided acceptable fo use in a pharmaceutical QCC lab related to M300?

    1 answer
    1. Methods of determination are provided on the Certificate of Analysis and are according to current compendial monographs. These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. The Quality designation of M300 is given according to our M-Clarity™ Program. M300 level products are for products used in applications requiring enhanced change control and quality agreements. For more information on the M-Clarity™ Program, visit the following link: https://www.sigmaaldrich.com/US/en/life-science/quality-and-regulatory-management/m-clarity-program

      Helpful?

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