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PHR1418

Supelco

Succinic Acid

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
Succinic acid, Butanedioic acid
Linear Formula:
HOOCCH2CH2COOH
CAS Number:
Molecular Weight:
118.09
Beilstein/REAXYS Number:
1754069
EC Number:
MDL number:
PubChem Substance ID:

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to USP 1623411

API family

succinic acid

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

235 °C (lit.)

mp

184-186 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

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This Item
49893797987398055
Succinic Acid Pharmaceutical Secondary Standard; Certified Reference Material

PHR1418

Succinic Acid

Succinic acid certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

49893

Succinic acid

Succinic acid anhydrous, free-flowing, Redi-Dri™, ACS reagent, ≥99.0%

797987

Succinic acid

Succinic acid ACS reagent, ≥99.0%

398055

Succinic acid

application(s)

pharmaceutical (small molecule)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

application(s)

-

application(s)

-

format

neat

format

neat

format

-

format

-

Quality Level

300

Quality Level

300

Quality Level

200

Quality Level

200

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, TraceCERT®

grade

ACS reagent, anhydrous

grade

ACS reagent

storage temp.

2-30°C

storage temp.

-

storage temp.

-

storage temp.

-

General description

Succinic acid is a dicarboxylic acid, which is used primarily as an acidity regulator in the food and beverage industry. Pharmaceutically, it is usually used as a conjugate feeder acid to form succinate salt and as an excipient.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Succinic acid may be used as a pharmaceutical reference standard for the determination of the analyte in raw material, food and pharmaceutical formulations by high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2952 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Improving pharmacy students' understanding and long-term retention of acid-base chemistry
Roche VF
American journal of pharmaceutical education, 71(6), 122-122 (2007)
Succinic acid
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 39(2), 6012-6012 (2018)
A new HPLC method for simultaneously measuring chloride, sugars, organic acids and alcohols in food samples
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J. Food Compos. Anal., 56(1-2), 25-33 (2017)
Simultaneous HPLC determination of organic acids, sugars and alcohols
Doyon G
Can. Inst. Food Sci Technol. J., 24(1-2), 87-94 (1991)
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