MilliporeSigma
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PHR1418

Supelco

Succinic Acid

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
Succinic acid, Butanedioic acid
Linear Formula:
HOOCCH2CH2COOH
CAS Number:
Molecular Weight:
118.09
Beilstein:
1754069
EC Number:
MDL number:
PubChem Substance ID:

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to USP 1623411

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

235 °C (lit.)

mp

184-186 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

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General description

Succinic acid is a dicarboxylic acid, which is used primarily as an acidity regulator in the food and beverage industry. Pharmaceutically, it is usually used as a conjugate feeder acid to form succinate salt and as an excipient. [1][2]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Succinic acid may be used as a pharmaceutical reference standard for the determination of the analyte in raw material, food and pharmaceutical formulations by high performance liquid chromatography.[3][4][5][6][7][8]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2952 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

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