PHR1423

Sodium Nitroprusside

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Sodium nitroferricyanide(III) dihydrate, Nitroprusside sodium, SNP, Sodium nitroprusside, Sodium pentacyanonitrosylferrate
• Linear Formula: Na₂[Fe(CN)₅NO] · 2H₂O
• CAS Number: 13755-38-9
• Molecular Weight: 297.95
• EC Number: 238-373-9
• MDL number: MFCD00149192
• PubChem Substance ID: 329823392
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to USP 1614501
• API family: sodium nitroprusside
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: [Na+].[Na+].[H]O[H].[H]O[H].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N
• InChI: 1S/5CN.Fe.NO.2Na.2H2O/c5*1-2;;1-2;;;;/h;;;;;;;;;2*1H2/q;;;;;2*-1;2*+1;;
• InChI key: OIRZWVYIQXBRFC-UHFFFAOYSA-N

Description

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards. Sodium Nitroprusside is widely used as a drug to manage hypertension, via lowering elevated blood pressure by acting on the arteriolar smooth muscle.

Application

Sodium Nitroprusside may be used as a spectrophotometric reagent for the analysis of meloxicam in pharmaceutical formulations using spectrophotometric technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB7818 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301
• Precautionary Statements: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable