PHR1433

Ascorbyl Glucoside

Name: Ascorbyl Glucoside
Brand: SIAL
Price: 134 USD
Availability: InStock

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Ascorbyl Glucoside

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About This Item

Empirical Formula (Hill Notation):

C₁₂H₁₈O₁₁

CAS Number:

129499-78-1

Molecular Weight:

338.26

MDL number:

MFCD23701380

UNSPSC Code:

41116107

PubChem Substance ID:

329822597

NACRES:

NA.24

Key Documents

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grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

API family

ascorbyl glucoside

form

solid

CofA

current certificate can be downloaded

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(C1=O)O[C@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO

InChI

1S/C12H18O11/c13-1-3(15)9-8(19)10(11(20)22-9)23-12-7(18)6(17)5(16)4(2-14)21-12/h3-7,9,12-19H,1-2H2/t3-,4+,5+,6-,7+,9+,12+/m0/s1

InChI key

MLSJBGYKDYSOAE-DCWMUDTNSA-N

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Analytical Reference Materials for Pharma QC

Certified Reference Materials

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Show Differences

1 of 4

This Item	PHR1455	PHR1008	PHR1709
Supelco PHR1433 Ascorbyl Glucoside	Supelco PHR1455 Ascorbyl Palmitate	Supelco PHR1008 Ascorbic Acid	Supelco PHR1709 Ascorbic Acid Impurity D
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) food and beverages	application(s) pharmaceutical (small molecule)
format neat	format neat	format neat	format neat
form solid	form -	form solid	form -
Quality Level 300	Quality Level 300	Quality Level 300	Quality Level 300
grade certified reference material, pharmaceutical secondary standard	grade certified reference material, pharmaceutical secondary standard	grade certified reference material, pharmaceutical secondary standard	grade certified reference material, pharmaceutical secondary standard
storage temp. 2-30°C	storage temp. 2-30°C	storage temp. 2-8°C	storage temp. 2-8°C

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ascorbyl Glucoside is used to protect skin from exposure to UV rays.[1]

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA2741 in the slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mass spectrometric stereoisomeric differentiation between α- and β-ascorbic acid 2-O-glucosides. Experimental and density functional theory study.

Basem Kanawati et al.

Rapid communications in mass spectrometry : RCM, 25(6), 806-814 (2011-02-22)

L-Ascorbic acid and two distinct anomers, namely the α-D-glucopyranosyl and β-D-glucopyranosyl-(1→2)-L-ascorbic acid (stereoisomers), were studied within the scope of collision-induced dissociation (CID) experiments, performed by linear ion acceleration and collision with argon atoms inside a hexapole quadrupole hexapole ion beam

Monoacylation of 2-O-alpha-D-glucopyranosyl-L-ascorbic acid by protease in N,N-dimethylformamide with low water content.

Akihiro Tai et al.

Carbohydrate research, 345(12), 1658-1662 (2010-06-23)

2-O-alpha-D-Glucopyranosyl-L-ascorbic acid (AA-2G) laurate was synthesized from AA-2G and vinyl laurate with a protease from Bacillus subtilis in N,N-dimethylformamide (DMF) with low water content. Addition of water to DMF dramatically enhanced monoacyl AA-2G synthesis. Maximum synthetic activity was observed when

Fractional carbon dioxide laser treatment to enhance skin permeation of ascorbic acid 2-glucoside with minimal skin disruption.

Chien-Yu Hsiao et al.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 38(8), 1284-1293 (2012-06-08)

Topical treatment with vitamin C has been used to treat photoaged skin and as a skin whitener, but no standard procedure exists for percutaneous delivery. To compare skin histology and the permeation of ascorbic acid 2-glucoside (AA2G) after fractional and

Site-saturation engineering of lysine 47 in cyclodextrin glycosyltransferase from Paenibacillus macerans to enhance substrate specificity towards maltodextrin for enzymatic synthesis of 2-O-D-glucopyranosyl-L-ascorbic acid (AA-2G).

Ruizhi Han et al.

Applied microbiology and biotechnology, 97(13), 5851-5860 (2012-11-07)

In this work, the site-saturation engineering of lysine 47 in cyclodextrin glycosyltransferase (CGTase) from Paenibacillus macerans was conducted to improve the specificity of CGTase towards maltodextrin, which can be used as a cheap and easily soluble glycosyl donor for the

Ascorbic acid 2-glucocide reduces micronucleus induction in distant splenic T lymphocytes following head irradiation.

Yuko Kinashi et al.

Mutation research, 695(1-2), 69-74 (2009-12-17)

Evidence from in vivo studies suggests there are enhanced radiation effects in abscopal regions after local head gamma ray irradiation. Splenocyte apoptosis and T lymphocyte micronuclei were induced at higher rates than what would be estimated given the dose at

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Ascorbyl Glucoside