This product is intended for use as an analytical standard. It has not been tested for solubility. The research grade product A4571 is the identical compound. This item is tested for solubility at 50 mg/ml in water. Available literature states that Warfarin Sodium is soluble in DMSO at 60 mg/ml, as well as ethanol.
PHR1435
Warfarin Sodium
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
3-(α-Acetonylbenzyl)-4-hydroxycoumarin sodium salt, 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
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About This Item
Linear Formula:
C19H15O4Na
CAS Number:
Molecular Weight:
330.31
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
204-929-4
MDL number:
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InChI key
KYITYFHKDODNCQ-UHFFFAOYSA-M
InChI
1S/C19H16O4.Na/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22;/h2-10,15,21H,11H2,1H3;/q;+1/p-1
SMILES string
[Na].CC(=O)CC(c1ccccc1)C2=C(O)c3ccccc3OC2=O
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. W0100000, traceable to USP 1719000
API family
warfarin
CofA
current certificate can be downloaded
packaging
pkg of 1 g
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
Gene Information
human ... VKORC1(79001)
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This Item | |||
|---|---|---|---|
| application(s) pharmaceutical (small molecule) | application(s) agriculture | application(s) pharmaceutical (small molecule) | application(s) pharmaceutical (small molecule) |
| technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) HPLC: suitable, gas chromatography (GC): suitable |
| format neat | format neat | format neat | format neat |
| Quality Level 300 | Quality Level 100 | Quality Level 300 | Quality Level 300 |
| grade certified reference material, pharmaceutical secondary standard | grade analytical standard | grade certified reference material, pharmaceutical secondary standard | grade certified reference material, pharmaceutical secondary standard |
| storage temp. 2-8°C | storage temp. - | storage temp. 2-30°C | storage temp. 2-8°C |
General description
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards. Warfarin Sodium is an anticoagulant rodenticide, commonly used for the control of rodents such as rats, mice, etc. in surroundings, commercial and industrial sites.
Application
Warfarin Sodium may be used pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using square-wave adsorptive cathodic stripping voltammetry.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA2743 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - Aquatic Chronic 3 - Repr. 1B
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Urszula Śliwińska-Hill et al.
Journal of biomolecular structure & dynamics, 37(14), 3731-3739 (2018-09-22)
The interaction between glycated human serum albumin (gHSA) and folic acid (FA) was investigated by various spectroscopic techniques, such as fluorescence, circular dichroism, UV-vis absorption spectroscopy and electrophoretic light scattering technique. These methods characterize the binding properties of an albumin-folic
Sittig's Handbook of Pesticides and Agricultural Chemicals (2014)
Colby A Nadeau et al.
Translational stroke research, 10(3), 287-297 (2018-06-28)
Intracerebral hemorrhage (ICH) causes blood-brain barrier (BBB) damage along with altered element levels in the brain. BBB permeability was quantified at 3, 7, and 14 days with Evans Blue dye after collagenase-induced ICH in rat. At peak permeability (day 3), a
Lippincott's Review for NCLEX-RN, 511(1), 63-69 (2005)
Analytical Methods for Therapeutic Drug Monitoring and Toxicology (2011)
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