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PHR1488

Supelco

Quercetin

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
Quercetin hydrate
Empirical Formula (Hill Notation):
C15H10O7 · xH2O
CAS Number:
Molecular Weight:
302.24 (anhydrous basis)
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

certified reference material
pharmaceutical secondary standard

CofA

current certificate can be downloaded

packaging

pkg of 1 g

application(s)

HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Pharmaceutical (small molecule)

format

neat

pharmacopeia traceability

traceable to PhEur Y0001009
traceable to USP 1592409

SMILES string

[H]O[H].Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3ccc(O)c(O)c3

InChI

1S/C15H10O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,16-19,21H;1H2

InChI key

OKXFBEYCJRMINR-UHFFFAOYSA-N

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General description

Quercetin is a flavanol with strong antioxidant property. Due to the ability to scavenge free radicals and bind transition metal ions, quercetin is commonly used as a nutritional supplement and physiochemical remedy for a large number of diseases.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Quercetin may be used as a pharmaceutical reference standard for the analysis of the analyte in biological samples and pharmaceutical formulations by high performance liquid chromatography (HPLC) and spectrophotometric methods.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB7760 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Certificate of Analysis

Certificate of Origin

Determination of quercetin and kaempferol in human urine after orally administrated tablet of ginkgo biloba extract by HPLC
Wang FM, et al.
Journal of Pharmaceutical and Biomedical Analysis, 33(2), 317-321 (2003)
Simultaneous spectrophotometric determination of rutin, quercetin and ascorbic acid in drugs using a Kalman Filter approach
Hassan HNA, et al.
Journal of Pharmaceutical and Biomedical Analysis, 20(1-2), 315-320 (1999)
Gabriella Testa et al.
PloS one, 9(5), e96795-e96795 (2014-05-08)
Chronic inflammatory events appear to play a fundamental role in Alzheimer's disease (AD)-related neuropathological changes, and to result in neuronal dysfunction and death. The inflammatory responses observed in the AD brain include activation and proliferation of glial cells, together with...
Guozheng Huang et al.
European journal of medicinal chemistry, 81, 15-21 (2014-05-14)
Two sets of carbamates based on the natural alkaloid evodiamine were designed, synthesized and evaluated as potential butyrylcholinesterase inhibitors. Although a set of carbamates of 3-hydroxyevodiamine (10a-f) is inactive both at AChE and BChE, carbamates of 5-deoxo-3-hydroxyevodiamine (11a-f) exhibit much...
Ouissame Bounedjah et al.
Nucleic acids research, 42(13), 8678-8691 (2014-07-12)
The sequence of events leading to stress granule assembly in stressed cells remains elusive. We show here, using isotope labeling and ion microprobe, that proportionally more RNA than proteins are present in stress granules than in surrounding cytoplasm. We further...

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