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PHR1561

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Tetrahydrofuran

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
Tetrahydrofuran, Butylene oxide, Oxolane, Tetramethylene oxide
Empirical Formula (Hill Notation):
C4H8O
CAS Number:
Molecular Weight:
72.11
Beilstein/REAXYS Number:
102391
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to USP 1601770

vapor density

2.5 (vs air)

vapor pressure

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

CofA

current certificate can be downloaded

autoignition temp.

610 °F

expl. lim.

1.8-11.8 %

packaging

ampule of 3x1.2 mL each

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.407 (lit.)

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

density

0.889 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

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1 of 4

This Item
RTC00008867676478445
Tetrahydrofuran Pharmaceutical Secondary Standard; Certified Reference Material

PHR1561

Tetrahydrofuran

-
Tetrahydrofuran Pharmaceutical Secondary Standard; Certified Reference Material

RTC000088

Tetrahydrofuran

-
Tetrahydrofuran ACS reagent, ≥99.0%, contains 250 ppm BHT as inhibitor

676764

Tetrahydrofuran

Essential Grade
Tetrahydrofuran analytical standard

78445

Tetrahydrofuran

-
application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

format

-

format

-

format

neat

Quality Level

300

Quality Level

300

Quality Level

-

Quality Level

100

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

grade

ACS reagent

grade

analytical standard

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

-

storage temp.

-

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Tetrahydrofuran is a saturated cyclic ether with a potential use as a biofuel. It is used for the manufacture of polyurethanes.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC0275 in the slot below. This is an example certificate only and may not be the lot that you receive.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2

supp_hazards

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

-6.2 °F - closed cup

flash_point_c

-21.2 °C - closed cup


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Szycher's Handbook of Polyurethanes (1999)
Fabrice Giusti et al.
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Articles

Butyl methyl ether; Acetic acid; 2-Butanone; Ethyl acetate; Tetrahydrofuran; 1-Butanol; Isopropyl acetate; Heptane; Propyl acetate; 3-Methylbutanol; 4-Methyl-2-pentanone; Isobutyl acetate; Butyl acetate; Dimethyl sulfoxide; Anisole; Cumene

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