PHR1689

Ammonium Glycyrrhizate

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Glycyrrhizic acid ammonium salt
• Empirical Formula (Hill Notation): C₄₂H₆₂O₁₆ · NH₃
• CAS Number: 53956-04-0
• Molecular Weight: 839.96
• NACRES: NA.24
• PubChem Substance ID: 329823557
• UNSPSC Code: 41116107
• EC Number: 258-887-7
• MDL number: MFCD00167400

Properties

• InChI key: ILRKKHJEINIICQ-OOFFSTKBSA-N
• InChI: 1S/C42H62O16.H3N/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50;/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54);1H3/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+;/m0./s1
• SMILES string: N.CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]3(C)[C@@H]2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@@]34C)C(O)=O)O[C@H]6O[C@@H]([C@@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)C(O)=O)C(O)=O
• grade: certified reference material, pharmaceutical secondary standard
• agency: traceable to Ph. Eur. G0460000, traceable to USP 1029929
• API family: glycyrrhizic acid
• CofA: current certificate can be downloaded
• packaging: pkg of 200 mg
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• Quality Level: 300

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ammonium Glycyrrhizate is the ammonium salt of glycyrrhizic acid (GA), an important ingredient in the liquorice root with a broad-spectrum of biological and pharmacological properties.[1]

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC3160 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable