PHR1695

Phenylephrine Related Compound C

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Phenylephrone hydrochloride, 1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride, 3′-Hydroxyphenyl-2-methylaminoacetophenone hydrochloride
• Empirical Formula (Hill Notation): C₉H₁₁NO₂ · HCl
• CAS Number: 94240-17-2
• Molecular Weight: 201.65
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• Quality Level: 300
• grade: certified reference material, pharmaceutical secondary standard
• agency: traceable to USP 1533024
• API family: phenylephrine
• CofA: current certificate can be downloaded
• packaging: pkg of 50 mg
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: [Cl-].N(CC(=O)c1cc(ccc1)O)C.[H+]
• InChI: 1S/C9H11NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,10-11H,6H2,1H3;1H
• InChI key: DEOGEZWYKPQJLP-UHFFFAOYSA-N

Description

General description

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

It is an impurity of the widely used decongestant drug― phenylephrine, a selective α1-adrenergic receptor agonist.

Application

This pharmaceutical secondary standard can also be used as follows:

• Impurity profiling of diphenhydramine and phenylephrine hydrochloride oral solutions using ultra-high performance liquid chromatography (UHPLC)

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

To see an example of a Certificate of Analysis for this material enter LRAC2623 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H317
• pcodes: P261 - P264 - P270 - P280 - P301 + P312 - P302 + P352
• Hazard Classifications: Acute Tox. 4 Oral - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable