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PHR1791

Ferulic Acid

Pharmaceutical Secondary Standard; Certified Reference Material

Ferulic Acid

Synonym(s):

trans-Ferulic acid, trans-4-Hydroxy-3-methoxycinnamic acid, Ferulic acid

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100 MG

$208.00

$208.00


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About This Item

Linear Formula:
HOC6H3(OCH3)CH=CHCO2H
CAS Number:
Molecular Weight:
194.18
Beilstein/REAXYS Number:
1570363
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

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grade

certified reference material
pharmaceutical secondary standard

Quality Level

agency

traceable to Ph. Eur. Y0001013
traceable to USP 1270311

API family

ferulic acid

CofA

current certificate can be downloaded

packaging

pkg of 100 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

168-172 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC(/C=C/C1=CC(OC)=C(O)C=C1)=O

InChI

1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+

Inchi Key

KSEBMYQBYZTDHS-HWKANZROSA-N

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1 of 4

This Item
1270311PHL8966346278
technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

MALDI-MS: suitable

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

food and beverages

application(s)

-

format

neat

format

neat

format

neat

format

-

Quality Level

300

Quality Level

-

Quality Level

-

Quality Level

100

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

primary reference standard

grade

matrix substance for MALDI-MS

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
This compound can be found as a component in plants of the genus: allium, angelica, cinnamomum, hedera, humulus, melissa, mentha, salvia, sambucus, thymus, zingiber

Application

Ferulic Acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations[1][2][3][4] by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Hydroxycinnamic acid found in plant-based foods. Antioxidant.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB6783 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simultaneous analysis of glycyrrhizin, paeoniflorin, quercetin, ferulic acid, liquiritin, formononetin, benzoic acid and isoliquiritigenin in the Chinese proprietary medicine Xiao Yao Wan by HPLC.
Xie J, et al.
Journal of Pharmaceutical and Biomedical Analysis, 45(3), 450-455 (2007)
High-performance liquid chromatographic method for the quantification of phenolics in `Chyavanprash?a potent Ayurvedic drug.
Govindarajan R, et al.
Journal of Pharmaceutical and Biomedical Analysis, 43(2), 527-532 (2007)
HPLC determination of ferulic acid in rat plasma after oral administration of Rhizoma Chuanxiong and its compound preparation.
Li Y and Bi K
Biomedical Chromatography, 17(8), 543-546 (2003)
Qualitative and quantitative analysis of the major constituents in Chinese medicinal preparation Guan-Xin-Ning injection by HPLC?DAD?ESI-MSn.
Ruan M, et al.
Journal of Pharmaceutical and Biomedical Analysis, 59(2), 184-189 (2012)
Sisir Kumar Barik et al.
The Journal of nutritional biochemistry, 78, 108325-108325 (2020-01-18)
The hypoglycaemic effects of two Ribes sp. i.e., anthocyanin-rich black currants (BC) were compared to green currants (GC), which are low in anthocyanins to establish which compounds are involved in the regulation of postprandial glycaemia. We determined the effect of

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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