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PHR1840

Supelco

Aminobenzoic Acid

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
4-Aminobenzoic acid, Vitamin H1, Vitamin Bx, PABA
Linear Formula:
H2NC6H4CO2H
CAS Number:
Molecular Weight:
137.14
Beilstein:
471605
EC Number:
MDL number:
NACRES:
NA.24

Quality Level

grade

certified reference material
pharmaceutical secondary standard

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

mp

187-189 °C (lit.)

density

1.374 g/mL at 25 °C (lit.)

application(s)

pharmaceutical

format

neat

pharmacopeia traceability

traceable to PhEur Y0000173
traceable to USP 1019803

storage temp.

2-30°C

SMILES string

Nc1ccc(cc1)C(O)=O

InChI

1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)

InChI key

ALYNCZNDIQEVRV-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Amiodarone is an antiarrhythmic agent used for the prophylaxis and treatment of ventricular arrhythmias and atrial fibrillation.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Aminobenzoic Acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical preparation by high performance liquid chromatographic method.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2774 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

339.8 °F

Flash Point(C)

171 °C

Certificate of Analysis

Certificate of Origin

Determination of nicotinamide and 4-aminobenzoic acid in pharmaceutical preparation by LC
Khan AR, et al.
Journal of Pharmaceutical and Biomedical Analysis, 29(4), 723-727 (2002)

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