This product has not been tested for solubility in DMSO. However, other sources report that L-α-Lysophosphatidylcholine is soluble in DMSO at less than 1.0 mg/mL. Higher rates may be achieved by utilizing other solvents. This material is commonly soluble in organic solvent mixtures. See below for solubility information available for research grade Lysophosphatidylcholine products:
Chloroform:methanol (1:1, v/v) 25-50 mg/mL
Ethanol 3.9 mg/mL
Chloroform 27.8 mg/mL
Methanol 14.6 mg/mL
PHR2631
Lysophosphatidylcholine
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
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| Size/SKU | Availability | Price |
|---|---|---|
250 mg | Check Cart for Availability | $256.00 $192.00 |
About This Item
$192.00
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Quality Segment
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. Y0001904, traceable to USP 1372050
API family
lysophosphatidylcholine
form
solid
packaging
pkg of 250 mg
application(s)
pharmaceutical small molecule
storage temp.
-10 to -25°C
General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions
Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun.
Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
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This Item | |||
|---|---|---|---|
| application(s) pharmaceutical small molecule | application(s) - | application(s) pharmaceutical small molecule | application(s) pharmaceutical (small molecule) |
| grade certified reference material, pharmaceutical secondary standard | grade - | grade certified reference material, pharmaceutical secondary standard | grade pharmaceutical primary standard |
| agency traceable to USP 1372050, traceable to Ph. Eur. Y0001904 | agency - | agency - | agency - |
| API family lysophosphatidylcholine | API family - | API family glutathione | API family lysophosphatidylcholine |
| packaging pkg of 250 mg | packaging - | packaging pkg of 100 mg | packaging - |
| form solid | form lyophilized powder | form solid | form - |
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Hello, is this product soluble in DMSO? If so, at what concentration? If not, which solvent(s) should be used to dissolve it? Thank you.
1 answer-
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