R8881

Rhodamine B isothiocyanate–Dextran

Powder

• Synonym(s): RITC-Dextran
• MDL number: MFCD00132176
• UNSPSC Code: 12171500
• NACRES: NA.47

Properties

• Product Name: Rhodamine B isothiocyanate–Dextran, average mol wt ~10,000
• form: powder
• Quality Level: 200
• mol wt: average mol wt ~10,000
• extent of labeling: 0.002-0.01 mol RITC per mol glucose
• technique(s): titration: suitable
• color: light pink to red; very dark purple
• solubility: water: 10 mg/mL, clear, pink
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: 2-8°C

Description

General description

Rhodamine B is a thiol-reactive and photostable fluorescent dye. Rhodamine B isothiocyanate is an aminoxanthene that possesses carboxylic acid and isothiocyanate substituents on the pendant phenyl ring.

Application

Dextran labeled with rhodamine B isothiocyanate for possible use in perfusion studies in animals.

Rhodamine B isothiocyanate (NE)-labeled dextran is often used as a fluorescent probe for studies of endocytotic activity and to detect the migrated of marked cells. It is also suitable for perfusion studies in animals. Rhodamine B isothiocyanate–Dextran has been used for in vivo zebrafish blood-brain barrier (BBB) dye diffusion assay.[1]

Biochem/physiol Actions

Rhodamine B stains the tissue in red-violet color and emits a bright red color when fluoresced. It is highly preferred for marking insects.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)