RDD036

BICINE

Redi-Dri^™, ≥99%, free-flowing

• Synonym(s): N,N-Bis(2-hydroxyethyl)glycine
• Empirical Formula (Hill Notation): C₆H₁₃NO₄
• CAS Number: 150-25-4
• Molecular Weight: 163.17
• NACRES: NA.21
• UNSPSC Code: 12161700
• Beilstein/REAXYS Number: 1769362
• MDL number: MFCD00004295

Properties

• product line: Redi-Dri^™
• Quality Segment: 100
• assay: ≥99%
• quality: free-flowing
• useful pH range: 7.6-9.0
• pKa (25 °C): 8.3
• SMILES string: OCCN(CCO)CC(O)=O
• InChI: 1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11)
• InChI key: FSVCELGFZIQNCK-UHFFFAOYSA-N

Description

General description

Bicine is an inorganic compound used to make Bicine buffer, a "Good buffer" that is commonly used in molecular biology and biochemistry. Bicine is a zwitterionic substituted glycine that is stable and soluble in water. It is has a pKa of 8.3, ideal for biological sytems with a pH range of 7.6 - 9.0.

Application

Redi-Dri^™ is an innovative packaging product line that helps eliminate clumping material by adding extra packaging process steps without any chemical additives, anti-clumping agents, or hydrophobic compounds. Redi Dri offers a more convenient and safer way to handle the products.

Recommended buffer for low temperature biochemical work. Used in the preparation of stable substrate solution for serum guanase determination. Spacer in plasma protein fractionation with Sephadex^® by isotachophoresis.

Bicine is typically used for protein analysis:

• for SDS-PAGE or Western blot assay, for column wash buffer, to pH solutions, to make digestion buffer for GFP & FRET Microscopy
• labeling buffer to prepare antibody solution for labeing for fluorecent assays

Features and Benefits

• Redi-Dri^™ design controls moisture for hygroscopic chemicals that commonly clump
• Anhydrous powder remains free-flowing and easy to use
• Eliminates clumps, for safer routine use in lab
• Maintains product moisture, quality, and attributes

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Sephadex is a registered trademark of Cytiva

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable