RDD040

Sodium dodecyl sulfate

BioReagent, suitable for electrophoresis, for molecular biology, ≥98.5% (GC), free-flowing, Redi-Dri^™

• Synonym(s): Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
• Linear Formula: CH₃(CH₂)₁₁OSO₃Na
• CAS Number: 151-21-3
• Molecular Weight: 288.38
• Beilstein/REAXYS Number: 3599286
• MDL number: MFCD00036175
• NACRES: NA.25

Properties

• grade: for molecular biology
• Quality Level: 100
• description: anionic
• product line: BioReagent; Redi-Dri^™
• assay: ≥98.5% (GC)
• quality: free-flowing
• mol wt: micellar 18,000
• aggregation number: 62
• technique(s): electrophoresis: suitable
• CMC: 7-10 mM (20-25°C)
• mp: 204-207 °C (lit.)
• transition temp: cloud point >100 °C
• solubility: water: soluble
• anion traces: chloride (Cl^-): ≤500 ppm; phosphate (PO₄^3-): ≤10 ppm
• cation traces: heavy metals (as Pb): ≤10 ppm
• absorption: ≤0.1 at 260 at 3%; ≤0.1 at 280 at 3%
• HLB: 40
• suitability: suitable for electrophoresis
• foreign activity: DNase, RNase, none detected
• SMILES string: [Na+].CCCCCCCCCCCCOS([O-])(=O)=O
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• InChI key: DBMJMQXJHONAFJ-UHFFFAOYSA-M

Description

General description

Sodium dodecyl sulfate (SDS) is an amphipathic detergent commonly used for denaturing proteins. SDS has a long-chain aliphatic group, with negatively charged sulfate groups that coat the surface of proteins, causing them to lose their quaternary structure.

Application

Sodium dodecyl sulfate has been used:

• in chromatin immunoprecipitation
• in SDS-polyacrylamide gel electrophoresis (SDS-PAGE)
• as a component of radioimmunoprecipitation assay buffer for immunoblotting

Anionic detergent

Analysis Note

Tested for use in denatured polyacrylamide gel electrophoresis.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• pictograms: GHS02,GHS05,GHS07
• signalword: Danger
• hcodes: H228,H302 + H332,H315,H318,H335,H412
• pcodes: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• wgk_germany: WGK 2
• flash_point_f: 338.0 °F
• flash_point_c: 170 °C