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S0450000

Serine

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

L-Serine, (S)-2-Amino-3-hydroxypropionic acid

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About This Item

Linear Formula:
HOCH2CH(NH2)CO2H
CAS Number:
56-45-1
Molecular Weight:
105.09
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329824426
MDL number:
MFCD00064224
Beilstein/REAXYS Number:
1721404

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InChI key

MTCFGRXMJLQNBG-REOHCLBHSA-N

SMILES string

N[C@@H](CO)C(O)=O

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

grade

pharmaceutical primary standard

API family

serine

manufacturer/tradename

EDQM

mp

222 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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1 of 4

This Item
PHR11031.07647S4311
Serine European Pharmacopoeia (EP) Reference Standard

S0450000

Serine

L-Serine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1103

L-Serine

L-Serine EMPROVE® EXPERT Ph Eur,USP

SAFC

1.07647

L-Serine

L-Serine from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

S4311

L-Serine

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

-

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

parenterals

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

-

format

-

API family

serine

API family

serine

API family

-

API family

-

mp

222 °C (dec.) (lit.)

mp

222 °C (dec.) (lit.)

mp

215-225 °C (decomposes)

mp

222 °C (dec.) (lit.)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Serine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Precursor of glycine by serine hydroxymethyltransferase.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

comparable product

Product No.
Description
Pricing

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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K U Sales et al.
Oncogene, 34(3), 346-356 (2014-01-29)
The membrane-anchored serine protease, matriptase, is consistently dysregulated in a range of human carcinomas, and high matriptase activity correlates with poor prognosis. Furthermore, matriptase is unique among tumor-associated proteases in that epithelial stem cell expression of the protease suffices to
Jacob T Bjerrum et al.
Inflammatory bowel diseases, 20(12), 2340-2352 (2014-10-31)
It is unknown why patients with extensive ulcerative colitis (UC) have a higher risk of colorectal cancer compared with patients with left-sided UC. This study characterizes the inflammatory processes in left-sided UC, pancolitis, and UC-associated dysplasia at the transcriptional level
Wei Wu et al.
Molecular cancer research : MCR, 12(12), 1717-1728 (2014-07-27)
Colorectal cancer metastasis is a major cause of mortality worldwide, which may only be controlled with novel methods limiting tumor dissemination and chemoresistance. High stathmin-1 (STMN1) expression was previously established as a hallmark of colorectal cancer progression and predictor of
Paul J M Wijnker et al.
Archives of biochemistry and biophysics, 554, 11-21 (2014-05-13)
Protein kinase C (PKC)-mediated phosphorylation of troponin I (cTnI) at Ser42/44 is increased in heart failure. While studies in rodents demonstrated that PKC-mediated Ser42/44 phosphorylation decreases maximal force and ATPase activity, PKC incubation of human cardiomyocytes did not affect maximal
Yunhua Zhu et al.
The Journal of clinical investigation, 124(7), 3263-3273 (2014-06-10)
The number of newly formed neurons declines rapidly during aging, and this decrease in neurogenesis is associated with decreased function of neural stem/progenitor cells (NPCs). Here, we determined that a WIP1-dependent pathway regulates NPC differentiation and contributes to the age-associated
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