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S0700000

Sodium calcium edetate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):
EDTA calcium disodium salt, Edathamil, (Ethylenedinitrilo)tetraacetic acid calcium disodium salt, Ethylenediaminetetraacetic acid calcium disodium salt
Linear Formula:
C10H12N2O8CaNa2
CAS Number:
Molecular Weight:
374.27
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Na+].[Na+].[Ca++].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.Ca.2Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;/q;+2;2*+1/p-4

InChI key

SHWNNYZBHZIQQV-UHFFFAOYSA-J

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors. As this form is already chelated with Ca2+, it is selective for divalent cations with greater affinity for EDTA, which it will exchange for Ca2+.

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Caution

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More documents

Quotes and Ordering

Sally Bradberry et al.
Clinical toxicology (Philadelphia, Pa.), 47(9), 841-858 (2009-10-27)
This article reviews the experimental and clinical studies that have compared the efficacy (impact on urine lead excretion, blood and tissue lead concentrations, resolution of features and survival) of sodium calcium edetate (edetate calcium disodium) and succimer (DMSA) in the
David Voglar et al.
Environmental technology, 35(9-12), 1389-1400 (2014-04-08)
We demonstrate here, in a pilot-scale experiment, the feasibility of ethylenediaminetetraacetate (EDTA)based washing technology for soils contaminated with potentially toxic metals. Acid precipitation coupled to initial alkaline toxic metal removal and an electrochemical advanced oxidation process were used for average
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Claudio Fozza et al.
Annals of hematology, 93(5), 899-900 (2013-10-02)
Il Joong Park et al.
Archives of pathology & laboratory medicine, 138(8), 1077-1082 (2014-07-31)
The Samsung LABGEO(HC10) Hematology Analyzer (LABGEO(HC10)) is a recently developed automated hematology analyzer that uses impedance technologies. The analyzer provides 18 parameters including 3-part differential at a maximum rate of 80 samples per hour. To evaluate the performance of the
Trial to Assess Chelation Therapy (TACT) and equipoise: When evidence conflicts with beliefs.
David J Maron et al.
American heart journal, 168(1), 4-5 (2014-06-24)

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