Sodium phosphate monobasic

ReagentPlus®, ≥99.0%

Monosodium phosphate, Sodium dihydrogen phosphate, Monosodium dihydrogen orthophosphate
Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

product line







DNA extraction: suitable
detection: suitable
electrophoresis: suitable
immunocytochemistry: suitable


4.0-4.5 (25 °C, 50 g/L in water)

pKa (25 °C)

(1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)


water: 100 mg/mL, clear, colorless

SMILES string




InChI key


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General description

Sodium phosphate monobasic acts as an acidulant in laxatives and effervescent powders. It is used in beverages, cheese and soft drink formulations.


Sodium phosphate monobasic has been used:
  • as a reagent for virus transfection and fiber implantation in mouse
  • in phosphate buffer for immunocytochemistry and to detect individual catalase activity by PAGE (polyacrylamide gel electrophoresis)
  • as a buffer for cycling assay
  • in automated DNA extraction method
  • as a chemical in artificial cerebro-spinal fluid (aCSF) solution for the preparation of brainstem-spinal cord from rats


3 kg in poly drum
1 kg in poly bottle
100, 500 g in poly bottle

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Detection of Catalase Activity by Polyacrylamide Gel Electrophoresis (PAGE) in Cell Extracts from Pseudomonas aeruginosa
Pezzoni M, et al.
Microbiology (2016)
Protocols to Study Declarative Memory Formation in Mice and Humans: Optogenetics and Translational Behavioral Approaches
Sellami A, et al.
Proceedings of the National Academy of Sciences of the USA (2017)
Automated and manual methods of DNA extraction for Aspergillus fumigatus and Rhizopus oryzae analyzed by quantitative real-time PCR
Francesconi A, et al.
Journal of Clinical Microbiology, 46(6), 1978-1984 (2008)
Dictionary of Food ingredients (2001)
In vitro Brainstem-spinal Cord Preparation from Newborn Rat
Le Gal JP, et al.
The Journal of Neuroscience (2016)
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