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S0930000

Sodium valproate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Valproic acid sodium salt, 2-propylpentanoic acid sodium, Sodium 2-propylpentanoate, Sodium valproate

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Pack SizeSKUAvailabilityPrice
50 mg
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$267.00

About This Item

Empirical Formula (Hill Notation):
C8H15NaO2
CAS Number:
Molecular Weight:
166.19
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:

$267.00


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grade

pharmaceutical primary standard

API family

sodium valproate

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Na+].CCCC(CCC)C([O-])=O

InChI

1S/C8H16O2.Na/c1-3-5-7(6-4-2)8(9)10;/h7H,3-6H2,1-2H3,(H,9,10);/q;+1/p-1

InChI key

AEQFSUDEHCCHBT-UHFFFAOYSA-M

Gene Information

human ... ALDH5A1(7915)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sodium valproate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Anti-convulsant that also has efficacy as a mood stabilizer in bipolar disorder.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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application(s)

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application(s)

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pharmaceutical small molecule

application(s)

pharmaceutical (small molecule)

API family

sodium valproate

API family

-

API family

valproic acid

API family

valproic acid

Gene Information

human ... ALDH5A1(7915)

Gene Information

human ... ALDH5A1(7915)

Gene Information

human ... ALDH5A1(7915)

Gene Information

human ... ALDH5A1(7915)


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pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Kristen A Wellmann et al.
Brain research bulletin, 108, 1-9 (2014-08-19)
Prenatal exposure to valproic acid (VPA) alters rodent social interactions in a dose-dependent way: exposure to a high dose of VPA (>500 mg/kg) mid-gestation decreases social interactions whereas a moderate dose of VPA (350 mg/kg) increases peer-directed social behavior. The
Pengfei Shi et al.
BMC cancer, 14, 370-370 (2014-06-03)
Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, is reported to exert anti-tumor effects by upregulating the expression of the natural killer group 2D (NKG2D) ligands on tumor cells; however, the mechanisms vary in different tumor types, and the effect
Péter Pelsőczi et al.
Frontiers in behavioral neuroscience, 13, 295-295 (2020-02-06)
Autism spectrum disorder (ASD) is characterized by impaired socio-communicational function, repetitive and restricted behaviors. Valproic acid (VPA) was reported to increase the prevalence of ASD in humans as a consequence of its use during pregnancy. VPA treatment also induces autistic-like



Global Trade Item Number

SKUGTIN
S093000004061836831004

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