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S6546

Sodium chloride solution

5 M

Sodium chloride solution

Synonym(s):

Halite, NaCl, sodium chloride

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Size/SKUAvailabilityPrice
1 L

Estimated to ship onJuly 22, 2026fromMILWAUKEE

$80.90
4 L

Available to ship TODAYfromMILWAUKEE

$269.00

About This Item

Linear Formula:
NaCl
CAS Number:
Molecular Weight:
58.44
UNSPSC Code:
12352302
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3534976

$80.90


Estimated to ship onJuly 22, 2026Details


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sterility

0.2 μm filtered

Quality Segment

concentration

5 M

density

1.190 g/cm3

SMILES string

[Na+].[Cl-]

InChI

1S/ClH.Na/h1H;/q;+1/p-1

InChI key

FAPWRFPIFSIZLT-UHFFFAOYSA-M

General description

Sodium chloride (NaCl), common salt also known as halite, is ubiquitous in occurrence and has many vital applications. It is a white crystalline solid, fairly soluble in water. NaCl is a flavouring agent in the food industry and used for texturing bread and baked foods. NaCl is an essential salt for normal body functions in humans and animals. NaCl is essential for maintaining plasma osmolality and extracellular fluid volume of the body. Excess of NaCl leads to elevated blood pressure which has implications on cardiovascular and renal diseases. NaCl is a basic component in the microbiological medium, specifically for culturing of halophiles. Sterile NaCl is a constituent of eye drop solutions.

Application

Sodium chloride has been used:
  • as a supplement in serum free media for CA3 pyramidal neuron layer preparation[1]
  • in the preparation of oligonucleotides (ODNs) annealing buffer
  • in the preparation of phosphate buffered saline and in phosphatase methylesterase-1 (PME-1) inhibition and counterscreen assay buffers

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description

5 M

description

5 M

description

BioUltra, Molecular Biology, ~5 M in H2O

description

0.85%

Quality Level

200

Quality Level

300

Quality Level

100

Quality Level

200

density

1.190 g/cm3

density

-

density

1.186 g/mL (5 M in water)

density

1.000 g/cm3 at 20 °C

concentration

5 M

concentration

5 M

concentration

~5 M in H2O

concentration

0.83-0.86% NaCl, 0.85%

sterility

0.2 μm filtered

sterility

sterile; sterile-filtered

sterility

-

sterility

-


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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Questions

1–4 of 4 Questions  
  1. What is the purity of the 5M NaCL? 99%?

    1 answer
    1. The purity of this solution is not determined. However, the purity of the sodium chloride used to prepare this product has a minimum purity of 99%.

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  3. Is this product endotoxin free? What is the EU/ml concentration?

    1 answer
    1. This product is not tested for endotoxin. Please see product S5150 at the link below. This product is an endotoxin tested, 5M Sodium Chloride Solution. The endotoxin specification for this item is <1 EU/m:L.
      https://www.sigmaaldrich.com/product/sigma/s5150

      Helpful?

  4. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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