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S7920

Sigma-Aldrich

Sodium fluoride

BioXtra, ≥99%

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Synonym(s):
NaF, Natrium fluoride, Sodium monoflouride
Linear Formula:
NaF
CAS Number:
Molecular Weight:
41.99
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

vapor pressure

1.4 mmHg ( 0 °C)

Quality Level

product line

BioXtra

Assay

≥99%

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

mp

993 °C (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.005%
sulfate (SO42-): ≤0.03%

cation traces

Al: ≤0.001%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.003%
K: ≤0.02%
Mg: ≤0.0005%
NH4+: ≤0.1%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

[F-].[Na+]

InChI

1S/FH.Na/h1H;/q;+1/p-1

InChI key

PUZPDOWCWNUUKD-UHFFFAOYSA-M

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This Item
215309SX0550450022
Sodium fluoride BioXtra, ≥99%

Sigma-Aldrich

S7920

Sodium fluoride

Premium Grade
Sodium fluoride 99.99% trace metals basis

Sigma-Aldrich

215309

Sodium fluoride

-
Sodium Fluoride Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs GR ACS

Supelco

SX0550

Sodium Fluoride

-
Sodium fluoride anhydrous, powder, 99.99% trace metals basis

Sigma-Aldrich

450022

Sodium fluoride

-
assay

≥99%

assay

99.99% trace metals basis

assay

≥99.5% (precipitation titration)

assay

99.99% trace metals basis

impurities

≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter

impurities

≤150.0 ppm Trace Metal Analysis

impurities

≤0.01% Insoluble matter, ≤0.04% Free alkali (as NaOH), ≤0.05% Free acid (as hydrofluoric acid), ≤0.1% Sodium fluosilicate (Na2SiF6)

impurities

≤150.0 ppm Trace Metal Analysis

mp

993 °C (lit.)

mp

993 °C (lit.)

mp

996 °C

mp

993 °C (lit.)

solubility

H2O: 1 M, clear, colorless

solubility

ethanol: insoluble(lit.)

solubility

soluble 42 g/L

solubility

-

anion traces

chloride (Cl-): ≤0.005%, sulfate (SO42-): ≤0.03%

anion traces

-

anion traces

chloride (Cl-): ≤0.003%, sulfate (SO42-): ≤0.01%, sulfite (SO32-): ≤0.005%

anion traces

-

Application

Sodium fluoride has been used:
  • as a source of fluoride ions, to analyse its impact on spermatogenesis and capacitation in vitro
  • as an additive in the extraction buffer for the isolation of nuclei, cytoplasmic and nuclear proteins
  • as a component of lysis buffer for the lysis of human ovarian adenocarcinoma OVCAR3 cells

Biochem/physiol Actions

Sodium fluoride (NaF) prevents dental caries, by catalysing the diffusion of calcium and phosphate and remineralizes the lesions. Fluoride affects spermatogenesis and capacitation process in the female reproductive tract. Fluoride induces oxidative stress, DNA damage in ovary ultimately affects the development of oocytes. Fluoride supplementation enhances bone mineral density. 18F-NaF is a radiotracer used in positron emission tomography (PET) to identify atherosclerotic lesions and other cardiac plaques.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Supplementary Hazards

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Dental caries
Selwitz RH, et al.
Lancet, 369(9555), 51-59 (2007)
Mangiferin induces apoptosis in human ovarian adenocarcinoma OVCAR3 cells via the regulation of Notch3
Zou B, et al.
Oncology Reports, 38(3), 1431-1441 (2017)
Fluoride-induced oxidative stress and apoptosis are involved in the reducing of oocytes development potential in mice
Wang HW, et al.
Chemosphere, 186, 911-918 (2017)
Toxicological Profile for Fluorides, Hydrogen Fluoride, and Fluorine (Update) (2011)
The influence of fluorides on mouse sperm capacitation
Dvorakova-Hortova K, et al.
Animal Reproduction Science, 108(1-2), 157-170 (2008)

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