The concentrations of bile acids are in the range of 700-900 nanomoles per milliliter for each bile acid. Accurate values are shown in the lot-specific Certificate of Analysis (COA), which is available in the documents section. The reagents specified in the protocol are important for product stability and extraction efficacy for plasma samples. These factors should also be considered when developing a method for fecal samples.
SMB00967
Bile Acids Standard Mixture
suitable for mass spectrometry (MS)
Synonym(s):
Deuterated Bile Acids mixture, standard mixture
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About This Item
UNSPSC Code:
12352211
NACRES:
NA.28
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technique(s)
mass spectrometry (MS): suitable
Quality Level
application(s)
lipidomics
metabolomics
shipped in
dry ice
storage temp.
−20°C
1 of 4
This Item | SMB00937 | 48305 | SMB00917 |
|---|---|---|---|
| technique(s) mass spectrometry (MS): suitable | technique(s) - | technique(s) - | technique(s) mass spectrometry (MS): suitable |
| application(s) lipidomics | application(s) - | application(s) microbiology | application(s) metabolomics |
| Quality Level 100 | Quality Level 100 | Quality Level 200 | Quality Level 100 |
| shipped in dry ice | shipped in - | shipped in - | shipped in wet ice |
| storage temp. −20°C | storage temp. -10 to -25°C | storage temp. 10-30°C | storage temp. 2-8°C |
General description
Bile acids are synthesized in the liver and play a crucial role in metabolic process (e.g., cholesterol and lipid metabolism) and liver health. They also regulate triglyceride, glucose and energy homeostasis etc. as a signaling molecule.
Application
The Bile acids isotopic labeled mixture is formulated for use as internal standard for high-through put LC/MS metabolomic analysis.
Features and Benefits
- All deuterated bile acids are dissolved in methanol and ready to use. Total vial volume is 1 mL.
- Simple mixture formulated to contain primary, secondary and conjugated bile acids.
- Ideal for LC-MS studies as internal standards.
- The mix can be used for targeted and untargeted approaches.
Analyte
Description
Taurochenodeoxycholic acid-d4
Glycochenodeoxycholic acid-d4
Glycocholic acid-d4
Cholic acid-d4
Chenodeoxycholic acid-d4
Deoxycholic acid-d4
Lithocholic acid-d4
Ursodeoxycholic acid-d4
See All (8)
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes,Central nervous system
Storage Class
3 - Flammable liquids
wgk_germany
WGK 2
flash_point_f
51.8 °F
flash_point_c
11 °C
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
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What is the total concentration of bile acids in the 1ml mixture? Is it even mandatory to get the products that are required and not provided in the kit even for faecal bile acid extraction for HPLC? Can we directly dilute the product and use it?
1 answer-
Helpful?
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what are the concentrations for these bile acids in the mixture?
1 answer-
The components are present in nanomolar quantities and each is reported in the product Certificate of Analysis. Please see the link below to review a sample or lot specific Certificate:
https://www.sigmaaldrich.com/product/sial/smb00967#product-documentationHelpful?
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Regarding the concentration, in the certificate of analysis it is reported as "nm". Does "nm" stay for "nmol/L", "nmol/mL", or "nmol"? Thank you for your support.
1 answer-
"nm" stands for nanomole per liter (nmol/L).
Helpful?
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What are the concentration of each standard in it. Provide the details. Thank you.
1 answer-
The concentration for each analyte is reported in the lot specific Certificate of Analysis. Concentrations are typically >750 nm for each. Please see the link below to review a sample or lot specific Certificate:
https://www.sigmaaldrich.com/product/sial/smb00967#product-documentationHelpful?
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