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MilliporeSigma

SMB00981

Sigma-Aldrich

2-Hydroxymelatonin

≥95% (HPLC)

Synonym(s):

2-OH MEL, 2-OHM, 2-OHMET, 2OHM, N-[2-(2,3-Dihydro-5-methoxy-2-oxo-1H-indol-3-yl)ethyl]acetamide, N-[2-(2-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide, AMIO

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About This Item

Empirical Formula (Hill Notation):
C13H16N2O3
CAS Number:
Molecular Weight:
248.28
MDL number:
UNSPSC Code:
12352205
NACRES:
NA.21

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Quality Level

assay

≥95% (HPLC)

form

solid

storage temp.

2-8°C

SMILES string

[nH]1c2c(c(c1O)CCNC(=O)C)cc(cc2)OC

InChI key

CIEAUFSGHUWAMC-UHFFFAOYSA-N

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1 of 4

This Item
SMB01350SMB01327PHR3700
assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

95% (HPLC)

assay

-

form

solid

form

solid

form

liquid

form

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

300

General description

Melatonin (MT) is metabolized into several derivatives, including N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK), N1-acetyl-5-methoxykynuramine (AMK), 6-hydroxymelatonin, 2-hydroxymelatonin, 3-hydroxymelatonin, and cyclic 3-hydroxymelatonin. MT and its metabolites are being studied for their antioxidant properties and their protective effects against oxidative stress in both mammals and in plants.

Application

Metabolomics research

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Questions

  1. I want to know the solvent and solubility of 2-hydroxymelatonin (SMB00981).

    1 answer
    1. The solubility of this material has not been determined. However, other sources report that this compound is soluble in methanol and in 2 mM MES, containing 5 mM MgCl2, pH 5.6. Please see the links below to review example publications:
      https://www.sciencedirect.com/science/article/pii/S025462992300594X
      https://pmc.ncbi.nlm.nih.gov/articles/PMC8614918/
      https://pmc.ncbi.nlm.nih.gov/articles/PMC9219689/

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