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greener alternative

average Mn ~1,150

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BRIJ® O20, Polyoxyethylene (20) oleyl ether
Linear Formula:
C18H35(OCH2CH2)nOH, n~20
CAS Number:
Molecular Weight:
MDL number:



Quality Level



mol wt

average Mn ~1,150

greener alternative product characteristics

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.


25-30 °C (lit.)

hydroxyl value

50‑65 mg KOH/g



greener alternative category



InChI key


General description

ECO Brij® O20, also known as oleyl alcohol polyoxyethylene ether, is a bio-based, high HLB nonionic surfactant manufactured from naturally occurring straight-chain oleyl alcohol. This detergent, derived from natural sources, provides various functional advantages, such as detergency, emulsification, and wetting, making it suitable for a range of applications in biochemical and biological research.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is a biobased surfactant and is aligned with the 7th principle of Green Chemistry "Use of Renewable Feedstocks" and the 10th principle "Design for Degradation".

Features and Benefits

  • 100 % Renewable
  • 100 % Bio-based
  • Certified to the USDA BioPreferred Program
  • Lower carbon footprint than petrochemical-based versions
  • High-purity chemical suitable for a wide variety of research applications

Legal Information

Brij is a registered trademark of Croda International PLC
ECO BRIJ is a registered trademark of Croda Inc.


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Signal Word


Hazard Statements

Hazard Classifications

Aquatic Chronic 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids



Flash Point(F)

464.0 °F - Equilibrium method

Flash Point(C)

> 240 °C - Equilibrium method

Certificates of Analysis (COA)

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Yash Kapoor et al.
Journal of colloid and interface science, 322(2), 624-633 (2008-03-25)
Surfactants are commonly incorporated into hydrogels to increase solute loading and attenuate the release rates. In this paper we focus on understanding and modeling the mechanisms of both surfactant and drug transport in hydrogels. Specifically, we focus on Brij 98
Carles Gil et al.
Biochemical and biophysical research communications, 348(4), 1334-1342 (2006-08-22)
Although the high presence of cholesterol in nerve terminals is well documented, specific roles of this lipid in transmitter release have remained elusive. Since cholesterol is a highly enriched component in the membrane microdomains known as lipid rafts, it is
Xi Chen et al.
Biochimica et biophysica acta, 1788(2), 477-483 (2009-01-03)
The size and the bilayer thickness of detergent-resistant membranes isolated from rat brain neuronal membranes using Triton X-100 or Brij 96 in buffers with or without the cations, K+/Mg2+ at a temperature of either 4 degrees C or 37 degrees
Jia-You Fang et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 67(1), 67-75 (2007-02-27)
Acoustically active lipospheres (AALs) were prepared using perfluorocarbons and coconut oil as the cores of inner phase. These AALs were stabilized using coconut oil and phospholipid coatings. A lipophilic antioxidant, resveratrol, was the model drug loaded into the AALs. AALs
Sergey Filippov et al.
Langmuir : the ACS journal of surfaces and colloids, 24(17), 9295-9301 (2008-08-09)
In this work we report a new type of pH-responsive micelle-like nanoparticle. Reversible nanoscale structures are formed in solutions of a pH-sensitive hydrophobic polyelectrolyte, poly( N-methacryloyl- l-valine) or poly( N-methacryloyl- l-phenylalanine), and nonionic surfactant (Brij 98) in the presence of

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