T19526

Tetramethylammonium chloride

reagent grade, ≥98%

• Synonym(s): TMA
• Linear Formula: (CH₃)₄N(Cl)
• CAS Number: 75-57-0
• Molecular Weight: 109.60
• Beilstein: 3911201
• EC Number: 200-880-8
• MDL number: MFCD00011628
• PubChem Substance ID: 57654658
• NACRES: NA.21

Properties

• grade: reagent grade
• Quality Level: 200
• Assay: ≥98%
• mp: >300 °C (lit.)
• SMILES string: [Cl-].C[N+](C)(C)C
• InChI: 1S/C4H12N.ClH/c1-5(2,3)4;/h1-4H3;1H/q+1;/p-1
• InChI key: OKIZCWYLBDKLSU-UHFFFAOYSA-M

Description

General description

Tetramethylammonium chloride is a quaternary ammonium salt commonly used as a catalyst due to its thermal stability and also tolerance towards strong aqueous bases or nucleophiles.

Application

Tetramethylammonium chloride along with N-hydroxyphthalimide and xanthone may be used as an efficient chloride catalytic system for the aerobic oxidation of hydrocarbons to form the corresponding oxygenated compounds. It may also be used as a phase transfer catalyst for the synthesis of aryl fluorides via selective chloride/fluoride exchange reaction of activated aryl chlorides with potassium fluoride in solid-liquid phase.

Safety Information

• Pictograms: GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H300 - H311 - H315 - H370 - H411
• Precautionary Statements: P260 - P264 - P273 - P280 - P301 + P310 - P302 + P352 + P312
• Hazard Classifications: Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Chronic 2 - Skin Irrit. 2 - STOT SE 1 Oral
• Target Organs: Central nervous system
• Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 1
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves