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MilliporeSigma

T8656

Thiourea

ACS reagent grade, ≥99.0%

Thiourea

Synonym(s):

Sulfourea, Thiocarbamide

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50 G

$62.30

100 G

$116.00

500 G

$168.00

$62.30


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About This Item

Linear Formula:
NH2CSNH2
CAS Number:
Molecular Weight:
76.12
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-543-5
MDL number:
Beilstein/REAXYS Number:
605327
Assay:
≥99.0%

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Product Name

Thiourea, ACS reagent, ≥99.0%

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

InChI key

UMGDCJDMYOKAJW-UHFFFAOYSA-N

SMILES string

NC(N)=S

grade

ACS reagent

assay

≥99.0%

ign. residue

≤0.1% (as SO4)

loss

≤0.5% loss on drying, 105°C, 2h

Quality Level

Gene Information

mouse ... Ephx2(13850)

mp

174-177 °C

solubility

H2O: passes test

functional group

amine, thiourea

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1 of 4

This Item
PHR17583088530-1940
assay

≥99.0%

assay

-

assay

≥99.999% (metals basis)

assay

≥98.0%

Quality Level

200

Quality Level

300

Quality Level

100

Quality Level

-

solubility

H2O: passes test

solubility

-

solubility

-

solubility

-

mp

170-176 °C (lit.)

mp

170-176 °C (lit.)

mp

170-176 °C (lit.)

mp

170-176 °C (lit.)

grade

ACS reagent

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

JIS special grade

ign. residue

≤0.1% (as SO4)

ign. residue

-

ign. residue

-

ign. residue

-

General description

Thiourea is an analogue of urea containing sulphur.[1]

Application

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins
Thiourea has been used:
  • as a component of lysis buffer for liver tissue homogenization[2]
  • in 2-D sample buffer for two-dimensional in-gel protein tyrosine phosphatases (PTP) assay[3]
  • in rehydration buffer for protein extraction[4]

Biochem/physiol Actions

Thiourea is a free radical scavenger of the peroxide radical.[2] It was shown to inhibit lipid peroxidation and ultraviolet (UV)-induced crosslinking of collagen. Bud dormancy in plants can be inhibited by thiourea which is used as a growth stimulator. It is also known to be used in the treatment of hyperthyroidism.[1]

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Effect of copper nanoparticles exposure in the physiology of the common carp (Cyprinus carpio): Biochemical, histological and proteomic approaches
Gupta YR, et al.
Aquaculture and Fisheries, 1(2), 15-23 (2016)
Investigation of protein-tyrosine phosphatases by in-gel assays.
Markova B, et al.
Methods, 35(1), 22-27 (2005)
Mechanism of the reduction of methylene blue by thiourea in aqueous acidic medium
Osunlaja AA
International Journal of ChemTech Research, 4(2), 609-617 (2012)
Yoshiji Takemoto
Chemical & pharmaceutical bulletin, 58(5), 593-601 (2010-05-13)
We have developed several multifunctional thiourea catalysts bearing a tertiary amine or an 1,2-amino alcohol in expectation of their synchronous activation of a nucleophile and an electrophile through both acid-base and hydrogen-bonding interactions. From these studies, it was revealed that
Elaine M Boyle et al.
The Journal of organic chemistry, 78(17), 8312-8319 (2013-08-01)
Thiourea-functionalized Tröger's base receptors 1 and 2 have been synthesized and evaluated as novel for the recognition of anions. Receptor 2 gave rise to significant changes in the absorption spectrum upon titration with AcO(-) and H2PO4(-) and acted as a

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      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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