Skip to Content
MilliporeSigma
All Photos(4)

Documents

U5128

Sigma-Aldrich

Urea

ACS reagent, 99.0-100.5%

Synonym(s):

Carbamide, Carbonyldiamide

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
NH2CONH2
CAS Number:
Molecular Weight:
60.06
Beilstein/REAXYS Number:
635724
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent

Quality Level

assay

≤0.001% (Heavy Metals by ICP-OES, metals basis)
99.0-100.5%

form

solid

impurities

≤0.01% Insoluble matter

ign. residue

≤0.01%

mp

132-135 °C (lit.)

solubility

H2O: soluble 480 g/L at 20 °C

density

1.335 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤5 ppm
sulfate (SO42-): ≤0.001%

cation traces

Fe: ≤0.001%

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

Gene Information

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Urea is a colourless organic compound, without any odour. It is easily soluble in water.

Application

Urea has been used:
  • to adjust the urea nitrogen concentration to a preferred range in blood reservoir for evaluating the dialyzer urea clearance
  • to prepare standards to measure urea synthesis
  • to prepare standards for blood urea nitrogen assay

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

Biochem/physiol Actions

Urea participates in the metabolism of nitrogenous substances. It serves as a nitrogen source, when used in fertilizers. Urea is used in manufacturing chemical compounds. It is widely used in the agricultural industry as a fertilizer as well as an animal feed additive, which is used as a nitrogen supplement in animal husbandry. Urea has adverse effects on seed germination, seedling growth and early plant growth in soil.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Hepatic targeting and biodistribution of human fetal liver stem/progenitor cells and adult hepatocytes in mice
Cheng K, et al.
Hepatology, 50(4), 1194-1203 (2009)
Urea: Synthesis, Properties and Uses (2012)
Elimination of the adverse effects of urea fertilizer on seed germination, seedling growth, and early plant growth in soil
Bremner JM and Krogmeier MJ
Proceedings of the National Academy of Sciences of the USA, 85(13), 4601-4604 (1988)
Hemodialyzer mass transfer-area coefficients for urea increase at high dialysate flow rates
Leypoldt JK, et al.
Kidney International, 51(6), 2013-2017 (1997)
CHAPTER 16 - METHODS OF FEEDING UREA TO LIVESTOCK
Urea As a Protein Supplement, 321-327 (1967)

Articles

A shortened review of fundamentals of Porous Graphitic Carbon (PGC) materials. What they are and how do they work as a stationary phase material in HPLC?.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service