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W450001

Sigma-Aldrich

Choline chloride

FCC

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Synonym(s):
(2-Hydroxyethyl)trimethylammonium chloride
Linear Formula:
(CH3)3N(Cl)CH2CH2OH
CAS Number:
Molecular Weight:
139.62
FEMA Number:
4500
Beilstein:
3563126
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

biological source

synthetic

Quality Level

grade

Halal
Kosher

reg. compliance

FCC
FDA 21 CFR 117

form

powder, crystals or chunks

color

white

mp

302-305 °C (dec.) (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

Organoleptic

fishy

SMILES string

[Cl-].C[N+](C)(C)CCO

InChI

1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1

InChI key

SGMZJAMFUVOLNK-UHFFFAOYSA-M

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1 of 4

This Item
C7017C752726978
Choline chloride FCC

Sigma-Aldrich

W450001

Choline chloride

-
Choline chloride ≥99%

Sigma-Aldrich

C7017

Choline chloride

-
Choline chloride BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98%

Sigma-Aldrich

C7527

Choline chloride

-
Choline chloride BioUltra, ≥99.0% (AT)

Sigma-Aldrich

26978

Choline chloride

Premium Grade
grade

Halal, Kosher

grade

-

grade

-

grade

-

mp

302-305 °C (dec.) (lit.)

mp

302-305 °C (dec.) (lit.)

mp

302-305 °C (dec.) (lit.)

mp

302-305 °C (dec.) (lit.)

documentation

see Safety & Documentation for available documents

documentation

-

documentation

-

documentation

-

food allergen

no known allergens

food allergen

-

food allergen

-

food allergen

-

organoleptic

fishy

organoleptic

-

organoleptic

-

organoleptic

-

General description

Choline chloride (ChCl) is a quaternary ammonium salt. The unusual solvent properties of eutectic mixtures of urea and choline chloride make it useful as a biodegradable ambient-temperature solvent for a number of applications.

Biochem/physiol Actions

The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes .

Substrates

Choline acetyltransferase substrate

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Andrew P Abbott et al.
Physical chemistry chemical physics : PCCP, 11(21), 4269-4277 (2009-05-22)
Here we describe for the first time the electrolytic deposition of copper and copper composites from a solution of the metal chloride salt in either urea-choline chloride, or ethylene glycol-choline chloride based eutectics. We show that the deposition kinetics and
Green and moisture-stable Lewis acidic ionic liquids (choline chloride.xZnCl2) catalyzed protection of carbonyls at room temperature under solvent-free conditions.
Duan Z, et al.
Catalysis Communications, 7, 651-656 (2006)
Determination of choline in milk, milk powder, and soy lecithin hydrolysates by flow injection analysis and amperometric detection with a choline oxidase based biosensor
Pati S, et al.
Journal of Agricultural and Food Chemistry, 52(15), 4638-4642 (2004)
Andrew P Abbott et al.
Chemical communications (Cambridge, England), (1)(1), 70-71 (2003-03-04)
Eutectic mixtures of urea and a range of quaternary ammonium salts are liquid at ambient temperatures and have interesting solvent properties.
Eutectic mixture of choline chloride/urea as a green solvent in synthesis of a coordination polymer:[Zn (O 3 PCH 2 CO 2)]? NH 4.
Liao JH, et al.
Inorganic Chemistry Communications, 8(4), 390-392 (2005)

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