The solubility of this product is not determined. However, the research-grade product M2574 is soluble in DMSO at ≥20 mg/mL. Other sources state the product can be solubilized in approximately 4 mg/mL of Ethanol or 87 mg/mL of Water.
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110 MG
$192.80
About This Item
Empirical Formula (Hill Notation):
C17H25N3O5S · 3H2O
CAS Number:
Molecular Weight:
437.51
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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Product Name
Meropenem trihydrate, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C17H25N3O5S.3H2O/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4;;;/h7-12,18,21H,5-6H2,1-4H3,(H,24,25);3*1H2/t7-,8-,9+,10+,11-,12-;;;/m1.../s1
SMILES string
O.O.O.C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(=O)N(C)C)=C(N2C1=O)C(O)=O
InChI key
CTUAQTBUVLKNDJ-OBZXMJSBSA-N
grade
pharmaceutical primary standard
API family
meropenem
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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1 of 4
This Item | 32460 | PHR1772 | M2574 |
|---|---|---|---|
| manufacturer/tradename EDQM | manufacturer/tradename - | manufacturer/tradename - | manufacturer/tradename - |
| grade pharmaceutical primary standard | grade analytical standard | grade certified reference material, pharmaceutical secondary standard | grade - |
| application(s) pharmaceutical (small molecule) | application(s) forensics and toxicology | application(s) pharmaceutical (small molecule) | application(s) - |
| format neat | format neat | format neat | format - |
| API family meropenem | API family - | API family meropenem | API family - |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C |
Application
Meropenem trihydrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Biochem/physiol Actions
Meropenem trihydrate is an ultra-broad spectrum beta-lactam antibiotic active against both Gram-positive and Gram-negative bacteria.
Meropenem trihydrate is an ultra-broad spectrum beta-lactam antibiotic.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
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signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Angelo Frei et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 26(13), 2852-2858 (2019-12-04)
New antibiotics and innovative approaches to kill drug-resistant bacteria are urgently needed. Metal complexes offer access to alternative modes of action but have only sparingly been investigated in antibacterial drug discovery. We have developed a light-activated rhenium complex with activity
Laurens Manning et al.
PloS one, 9(7), e102023-e102023 (2014-07-16)
Concerns regarding the clinical impact of meropenem instability in continuous infusion (CI) devices may contribute to inconsistent uptake of this method of administration across outpatient parenteral antimicrobial therapy (OPAT) services. We retrospectively reviewed the clinical efficacy and safety of CIs
Johannes Zander et al.
Clinical chemistry and laboratory medicine, 53(5), 781-791 (2014-10-11)
Recent studies have demonstrated highly variable blood concentrations of piperacillin, tazobactam, cefepime, meropenem, ciprofloxacin and linezolid in critically ill patients with a high incidence of sub-therapeutic levels. Consequently, therapeutic drug monitoring (TDM) of these antibiotics has to be considered, requiring
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bonjour, Je souhaiterai savoir dans quel tampon je peux dissoudre la poudre
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