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01148

Sodium fluoride

puriss., meets analytical specification of Ph. Eur., BP, USP, 98.5-100.5% (calc. to the dried substance)

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About This Item

Linear Formula:
NaF
CAS Number:
7681-49-4
Molecular Weight:
41.99
UNSPSC Code:
12352302
eCl@ss:
38050104
PubChem Substance ID:
329747226
EC Number:
231-667-8
NACRES:
NA.21
MDL number:
MFCD00003524
Assay:
98.5-100.5% (calc. to the dried substance)
Form:
powder

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InChI

1S/FH.Na/h1H;/q;+1/p-1

InChI key

PUZPDOWCWNUUKD-UHFFFAOYSA-M

vapor pressure

1.4 mmHg ( 0 °C)

grade

puriss.

assay

98.5-100.5% (calc. to the dried substance)

form

powder

quality

meets analytical specification of Ph. Eur., BP, USP

impurities

acidity or alkalinity, complies, organic volatile impurities, complies (GC), residual solvents, complies, ≤0.002% heavy metals (as Pb), ≤0.1% free alkali (as NaOH), ≤0.2% free acid (as HF), ≤0.2% sodium hexafluorosilicate (Na2SiF6)

loss

≤0.5% loss on drying, 150 °C

mp

993 °C (lit.)

anion traces

chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤200 mg/kg

cation traces

Fe: ≤50 mg/kg

suitability

complies for appearance of solution

Quality Level

200

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1 of 4

This Item
201154450022PHR1408
Sodium fluoride puriss., meets analytical specification of Ph. Eur., BP, USP, 98.5-100.5% (calc. to the dried substance)

Sigma-Aldrich

01148

Sodium fluoride

Sodium fluoride ACS reagent, ≥99%

Sigma-Aldrich

201154

Sodium fluoride

Sodium fluoride powder, 99.99% trace metals basis

Sigma-Aldrich

450022

Sodium fluoride

Sodium Fluoride Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1408

Sodium Fluoride

form

powder

form

powder

form

powder

form

-

assay

98.5-100.5% (calc. to the dried substance)

assay

≥99%

assay

99.99% trace metals basis

assay

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

300

grade

puriss.

grade

-

grade

-

grade

-

mp

993 °C (lit.)

mp

993 °C (lit.)

mp

993 °C (lit.)

mp

993 °C (lit.)

anion traces

chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤200 mg/kg

anion traces

chloride (Cl-): ≤0.005%, sulfate (SO42-): ≤0.03%, sulfite (SO32-): ≤0.005%

anion traces

-

anion traces

-

General description

Sodium fluoride (NaF) is a metallic halide. It has been reported as dental caries preventive agent.[1] It is the most widely employed preservative for glucose in blood.[2] It has been reported to stabilize hepatic microsomal glucose-6-P phosphohydrolase enzyme.[3]

Application

Sodium fluoride may be employed as fluorination agent in the synthesis of aromatic and aliphatic fluorides, via metathesis.[4] It may be used to prepare the lysis buffer.[5]

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

supp_hazards

EUH032

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

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Certificates of Analysis (COA)

Lot/Batch Number
STBL0919
STBK6711
STBK4579
STBK4450
STBK3254

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Effectiveness of sodium fluoride as a preservative of glucose in blood.
Chan AY, et al.
Clinical Chemistry, 35(2), 315-317 (1989)
A J Lange et al.
The Journal of biological chemistry, 261(1), 101-107 (1986-01-05)
Stabilization and inhibition of hepatic microsomal glucose-6-P phosphohydrolase (EC 3.1.3.9) by F- requires the presence of Al3+ ions. At millimolar concentrations, reagent grade NaF inhibited glucose-6-P hydrolysis and protected the enzyme against inactivation induced by heat in the presence of
J G Drachman et al.
The Journal of biological chemistry, 270(10), 4979-4982 (1995-03-10)
c-Mpl is a member of the cytokine receptor superfamily, expressed primarily on hematopoietic cells. Recently, the c-Mpl ligand was cloned and found to have thrombopoietic activity. In this paper we report that ligand binding induced tyrosine phosphorylation in BaF3 cells
Synthesis of fluorides by metathesis with sodium fluoride.
Tullock CW and Coffman DD.
The Journal of Organic Chemistry, 25(11), 2016-2019 (1960)
Hye-Jin Lee et al.
The Kaohsiung journal of medical sciences, 31(6), 303-308 (2015-06-05)
Dental caries preventive agents, such as sodium fluoride (NaF) and bamboo salt (BS), are known to cause cellular growth that is characterized by morphological and gene expression changes. This study was designed to investigate the dual effect of NaF and
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