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01148

Sigma-Aldrich

Sodium fluoride

puriss., 98.5-100.5% (calc. to the dried substance), meets analytical specification of Ph. Eur., BP, USP

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Linear Formula:
NaF
CAS Number:
Molecular Weight:
41.99
EC Number:
MDL number:
eCl@ss:
38050104
PubChem Substance ID:
NACRES:
NA.21

vapor pressure

1.4 mmHg ( 0 °C)

Quality Level

grade

puriss.

assay

98.5-100.5% (calc. to the dried substance)

form

powder

quality

meets analytical specification of Ph. Eur., BP, USP

impurities

acidity or alkalinity, complies
organic volatile impurities, complies (GC)
residual solvents, complies
≤0.002% heavy metals (as Pb)
≤0.1% free alkali (as NaOH)
≤0.2% free acid (as HF)
≤0.2% sodium hexafluorosilicate (Na2SiF6)

loss

≤0.5% loss on drying, 150 °C

mp

993 °C (lit.)

anion traces

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤200 mg/kg

cation traces

Fe: ≤50 mg/kg

suitability

complies for appearance of solution

SMILES string

[F-].[Na+]

InChI

1S/FH.Na/h1H;/q;+1/p-1

InChI key

PUZPDOWCWNUUKD-UHFFFAOYSA-M

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1 of 4

This Item
2011542153091.93670
vibrant-m

01148

Sodium fluoride

Essential Grade
vibrant-m

201154

Sodium fluoride

-
vibrant-m

215309

Sodium fluoride

-
vibrant-m

1.93670

Sodium fluoride

-
assay

98.5-100.5% (calc. to the dried substance)

assay

≥99%

assay

99.99% trace metals basis

assay

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

grade

puriss.

grade

-

grade

-

grade

-

impurities

acidity or alkalinity, complies, residual solvents, complies, ≤0.1% free alkali (as NaOH), ≤0.2% sodium hexafluorosilicate (Na2SiF6), organic volatile impurities, complies (GC), ≤0.2% free acid (as HF), ≤0.002% heavy metals (as Pb)

impurities

≤0.01 meq/g Titr. base, ≤0.02% insolubles, ≤0.03 meq/g Titr. acid, ≤0.1% sodium fluorosilicate

impurities

≤150.0 ppm Trace Metal Analysis

impurities

-

anion traces

chloride (Cl-): ≤100 mg/kg, sulfate (SO42-): ≤200 mg/kg

anion traces

chloride (Cl-): ≤0.005%, sulfate (SO42-): ≤0.03%, sulfite (SO32-): ≤0.005%

anion traces

-

anion traces

-

General description

Sodium fluoride (NaF) is a metallic halide. It has been reported as dental caries preventive agent. It is the most widely employed preservative for glucose in blood. It has been reported to stabilize hepatic microsomal glucose-6-P phosphohydrolase enzyme.

Application

Sodium fluoride may be employed as fluorination agent in the synthesis of aromatic and aliphatic fluorides, via metathesis. It may be used to prepare the lysis buffer.

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

supp_hazards

Storage Class

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Customers Also Viewed

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Effectiveness of sodium fluoride as a preservative of glucose in blood.
Chan AY, et al.
Clinical Chemistry, 35(2), 315-317 (1989)
Synthesis of fluorides by metathesis with sodium fluoride.
Tullock CW and Coffman DD.
The Journal of Organic Chemistry, 25(11), 2016-2019 (1960)
A J Lange et al.
The Journal of biological chemistry, 261(1), 101-107 (1986-01-05)
Stabilization and inhibition of hepatic microsomal glucose-6-P phosphohydrolase (EC 3.1.3.9) by F- requires the presence of Al3+ ions. At millimolar concentrations, reagent grade NaF inhibited glucose-6-P hydrolysis and protected the enzyme against inactivation induced by heat in the presence of
J G Drachman et al.
The Journal of biological chemistry, 270(10), 4979-4982 (1995-03-10)
c-Mpl is a member of the cytokine receptor superfamily, expressed primarily on hematopoietic cells. Recently, the c-Mpl ligand was cloned and found to have thrombopoietic activity. In this paper we report that ligand binding induced tyrosine phosphorylation in BaF3 cells
Hye-Jin Lee et al.
The Kaohsiung journal of medical sciences, 31(6), 303-308 (2015-06-05)
Dental caries preventive agents, such as sodium fluoride (NaF) and bamboo salt (BS), are known to cause cellular growth that is characterized by morphological and gene expression changes. This study was designed to investigate the dual effect of NaF and

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