04243

Potassium phosphate monobasic

meets analytical specification of Ph. Eur., NF, E340, anhydrous, 98-100.5% (calc. to the dried substance)

• Synonym(s): Monopotassium phosphate, Potassium dihydrogen phosphate, prim.-Potassium phosphate
• Linear Formula: KH₂PO₄
• CAS Number: 7778-77-0
• Molecular Weight: 136.09
• EC Number: 231-913-4
• MDL number: MFCD00011401
• eCl@ss: 38070209
• PubChem Substance ID: 329747897
• NACRES: NA.25

Properties

• grade: anhydrous
• Quality Level: 200
• Assay: 98-100.5% (calc. to the dried substance)
• form: crystalline
• quality: meets analytical specification of Ph. Eur., NF, E340
• impurities: org. volatile impurities, complies (GC); residual solvents, complies; ≤0.001% heavy metals (as Pb); ≤0.04% KMnO₄ red. matter (as O); ≤0.2% in water insoluble matters
• loss: ≤1% loss on drying, 130 °C
• pH: 4.2-4.5 (20 °C, 5%)
• pKa (25 °C): (1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)
• mp: 252.6 °C (lit.)
• solubility: H₂O: soluble 4.5 parts; alcohol: insoluble
• density: 2.338 g/mL at 25 °C (lit.)
• anion traces: chloride (Cl^-): ≤10 mg/kg; fluoride (F^-): ≤10 mg/kg; sulfate (SO₄^2-): ≤200 mg/kg
• cation traces: As: ≤2 mg/kg; Cd: ≤1 mg/kg; Cu: ≤20 mg/kg; Fe: ≤10 mg/kg; Hg: ≤1 mg/kg; Na: ≤1000 mg/kg; Pb: ≤4 mg/kg; Zn: ≤20 mg/kg
• suitability: complies for appearance of solution
• SMILES string: [K+].OP(O)([O-])=O
• InChI: 1S/K.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1
• InChI key: GNSKLFRGEWLPPA-UHFFFAOYSA-M

Description

Application

Potassium phosphate monobasic was used for separating tobacco protein by using aqueous two-phase extraction.

Biochem/physiol Actions

Potassium phosphate monobasic also referred to as monopotassium phosphate or potassium dihydrogen phosphate is a soluble salt of potassium that serves as a buffering agent. It enhances the solubility of calcium and phosphorus in amino acid plus dextrose solutions and hence assists in improving the mineral balance of parenterally fed low birth weight infants.

Preparation Note

Potassium phosphate monobasic dissolves in 4.5 (approx.) parts of water to yield a solution. It is practically insoluble in alcohol.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable