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Sodium phosphate monobasic dihydrate

meets analytical specification of Ph. Eur., BP, USP, FCC, E 339, 98-100.5% (calc. to the dried substance)

Sodium dihydrogen phosphate dihydrate
Linear Formula:
NaH2PO4 · 2H2O
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


98-100.5% (calc. to the dried substance)


powder or crystals


meets analytical specification of Ph. Eur., BP, USP, FCC, E 339


heavy metals (as Pb), complies
organic volatile impurities, complies
reducing matter, complies
related substances, complies
residual solvents, complies
≤0.2% water-insoluble matter


21.5-24.0% loss on drying, 130 °C


4.1-5.0 (20 °C, 1%)
4.2-4.5 (20 °C, 5%)

anion traces

chloride (Cl-): ≤50 mg/kg
fluoride (F-): ≤10 mg/kg
sulfate (SO42-): ≤200 mg/kg

cation traces

Al:, in accordance
As: ≤1 mg/kg
Ca: ≤20 mg/kg
Ca:, in accordance
Cd: ≤1 mg/kg
Cu: ≤10 mg/kg
Fe: ≤5 mg/kg
Hg: ≤1 mg/kg
Mg: ≤20 mg/kg
Pb: ≤4 mg/kg
Zn: ≤10 mg/kg


complies for appearance of solution

SMILES string




InChI key


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This Item

powder or crystals






powder or crystals


heavy metals (as Pb), complies, organic volatile impurities, complies, reducing matter, complies, related substances, complies, residual solvents, complies, ≤0.2% water-insoluble matter


≤0.15% In water insoluble matter (calculated on dried substance)




DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected


4.1-5.0 (20 °C, 1%), 4.2-4.5 (20 °C, 5%)


4.5 (25 °C, 12 g/L in H2O)


4.0-4.5 (25 °C, 50 mg/mL in H2O)


4.0-4.5 (25 °C, 1 M in H2O)

anion traces

chloride (Cl-): ≤50 mg/kg, fluoride (F-): ≤10 mg/kg, sulfate (SO42-): ≤200 mg/kg

anion traces

chloride (Cl-): ≤0.0005%, fluoride (F-): ≤0.001%, phosphate, phosphite (as H3PO4): ≤0.5%, sulfate (SO42-): ≤0.01%

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Al:, in accordance, As: ≤1 mg/kg, Ca: ≤20 mg/kg, Ca:, in accordance, Cd: ≤1 mg/kg, Cu: ≤10 mg/kg, Fe: ≤5 mg/kg, Hg: ≤1 mg/kg, Mg: ≤20 mg/kg, Pb: ≤4 mg/kg, Zn: ≤10 mg/kg

cation traces

Al:, passes test (detectable with ammonia), As: ≤0.00005%, Ca: ≤0.005%, Ca:, passes test (detectable with ammonia), Cd: ≤0.0001%, Co: ≤0.005%, Cu: ≤0.005%, Fe: ≤0.001%, Hg: ≤0.0001%, K: ≤0.005%, Mg: ≤0.005%, N: ≤0.001%, Ni: ≤0.005%, Pb: ≤0.0004%, Zn: ≤0.025%, heavy metals (as Pb): ≤0.0005%

cation traces

Ca: ≤50 mg/kg, Cd: ≤50 mg/kg, Co: ≤50 mg/kg, Cu: ≤50 mg/kg, Fe: ≤50 mg/kg, K: ≤100 mg/kg, Ni: ≤50 mg/kg, Pb: ≤50 mg/kg, Zn: ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.2 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤200 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg


Sodium phosphate monobasic dihydrate has been used for preparing phosphate buffer solution. It has also been used as a mobile phase for high-performance liquid chromatography.

Biochem/physiol Actions

Sodium phosphate monobasic also referred to as sodium dihydrogen phosphate is a chemical reagent possesses high buffering capacity and is used for preparing biological buffers. It was used as a phosphate supplement for determining whether phosphate supplementation can prevent rickets in very low birth weight infants with prenatal deficiency of phosphate.

Storage Class Code

11 - Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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