155810

2-Methyltetrahydrofuran

BioRenewable, ReagentPlus^®, ≥99.5%, contains 150-400 ppm BHT as stabilizer

• Synonym(s): 2-MeTHF, Tetrahydrosilvan, Tetrahydro-2-methylfuran
• Empirical Formula (Hill Notation): C₅H₁₀O
• CAS Number: 96-47-9
• Molecular Weight: 86.13
• Beilstein: 102448
• EC Number: 202-507-4
• MDL number: MFCD00005367
• PubChem Substance ID: 329750937
• NACRES: NA.21

Properties

• Quality Level: 100
• product line: ReagentPlus^®
• assay: ≥99.5%
• form: liquid
• contains: 150-400 ppm BHT as stabilizer
• expl. lim.: 0.34-6.3 %
• greener alternative product characteristics: Safer Solvents and Auxiliaries; Use of Renewable Feedstocks; Learn more about the Principles of Green Chemistry.
• impurities: ≤1.0% water (coulometr.); ≤100 ppm peroxide (as H₂O₂)
• refractive index: n20/D 1.406 (lit.)
• bp: 78-80 °C (lit.)
• mp: -136 °C
• density: 0.86 g/mL at 25 °C (lit.)
• greener alternative category: Aligned, Aligned
• SMILES string: CC1CCCO1
• InChI: 1S/C5H10O/c1-5-3-2-4-6-5/h5H,2-4H2,1H3
• InChI key: JWUJQDFVADABEY-UHFFFAOYSA-N

Description

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a biorenewable and thus aligns with "Safer Solvents and Auxiliaries" and "Use of Renewable Feedstocks". Click here for more information.
2-Methyltetrahydrofuran is an environmentally favorable alternative to tetrahydrofuran (THF), 1,4 Dioxane (Dioxane) and dichloromethane (DCM) for most industrial applications.
Many of its benefits include:

• High boiling point
• Clean organic-water phase separation
• Reduced energy to recover

Application

Alternative for THF in Organometallic reactions:

• Grignard
• Reformantsky
• Lithiation
• Hydride Reduction
• Metal-Catalyzed Coupling (Heck, Stile, Suzuki)

Alternative to Dichloromethane for Biphasic Reactions:

• Alkylation
• Amidation
• Nucleophilic Substitution

Forms organic (non-crystalline) glass for low temperature (-196°C) spectroscopic studies.

Green Alternatives to DCM and THF from Renewable resources

2-Methyltetrahydrofuran (2-MeTHF): A Biomass-Derived Solvent with Broad Application in Organic Chemistry

Packaging

100, 500 mL in glass bottle

2.5, 4×4 L in glass bottle

18, 200 L in steel drum

Features and Benefits

BioRenewable
Replacement for THF, DCM, MTBE and DMSO

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Safety Information

• Pictograms: GHS02,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H225 - H302 - H315 - H318
• Precautionary Statements: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2
• Supplementary Hazards: EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK Germany: WGK 2
• Flash Point(F): 14.0 °F - closed cup
• Flash Point(C): -10.0 °C - closed cup