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185469

Sigma-Aldrich

2-Methoxyethanol

ReagentPlus®, ≥99.0%, contains 50 ppm BHT as stabilizer

Synonym(s):

Ethylene glycol monomethyl ether, Methyl glycol

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About This Item

Linear Formula:
CH3OCH2CH2OH
CAS Number:
Molecular Weight:
76.09
Beilstein/REAXYS Number:
1731074
EC Number:
MDL number:
UNSPSC Code:
12352112
PubChem Substance ID:
NACRES:
NA.21

vapor density

2.62 (vs air)

Quality Level

vapor pressure

6.17 mmHg ( 20 °C)

product line

ReagentPlus®

assay

≥99.0%

form

liquid

autoignition temp.

548 °F

contains

50 ppm BHT as stabilizer

expl. lim.

24.5 %

refractive index

n20/D 1.402 (lit.)

pH

5.0-7.0 (25 °C)

bp

124-125 °C (lit.)

mp

−85 °C (lit.)

density

0.965 g/mL at 25 °C (lit.)

SMILES string

COCCO

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI key

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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General description

2-Methoxyethanol is widely used solvent in various electrochemical studies and industrial processes. It exhibits “quasi-aprotic properties. Its solvent characteristics are a mixture of that of protic and aprotic solvents. Dissolution of alkali metal salts in 2-methoxyethanol and their conductance, viscosity and laser-Raman spectra have been evaluated.

Application


  • Enzymatic synthesis of a skin active ingredient - glochiDoneby 3-ketosteroid dehydrogenase from Sterolibacterium denitrificans: This study showcases the utility of 2-Methoxyethanol in enzymatic processes critical for the development of dermatological agents, providing a bridge between organic chemistry and bioapplications in material science (Wojtkiewicz et al., 2024).

  • Toxicity of organic solvents and surfactants to the sea urchin embryos: Demonstrates the environmental impact assessments of 2-Methoxyethanol, aligning with environmental safety protocols critical for lab technicians and researchers in eco-toxicology (Semenova et al., 2024).

  • Room-Temperature Processed Annealing-Free Printable Carbon-Based Mesoscopic Perovskite Solar Cells with 17.34% Efficiency: Highlights the use of 2-Methoxyethanol in the production of high-efficiency solar cells, relevant for material scientists and researchers in energy-related applications (Zhu et al., 2024).

  • Ce-doped MgO films on AZ31 alloy substrate for biomedical applications: Explores the preparation and characterization of materials using 2-Methoxyethanol, essential for researchers focusing on advanced biomedical applications and material science (Hattab et al., 2024).

  • Solution-Processed Sb(2)S(3)-Based Heterojunction for Self-Powered Broad Band Weak Light Detection: Discusses the role of 2-Methoxyethanol in developing photodetectors, important for researchers in photonic and semiconductor research sectors (Vishwanathan Vidyanagar et al., 2024).

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - Repr. 1B - STOT RE 2 - STOT SE 1

target_organs

Immune system, thymus

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

104.0 °F - closed cup

flash_point_c

40 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Conductometric, viscometric, and spectroscopic investigations on the solvation phenomena of alkali-metal ions and ion pairs in 2-methoxyethanol.
Das B and Hazra DK.
The Journal of Physical Chemistry, 99(1), 269-273 (1995)
Huiping Yang et al.
Cryobiology, 61(2), 211-219 (2010-07-27)
Medaka Oryzias latipes is a well-recognized biomedical fish model because of advantageous features such as small body size, transparency of embryos, and established techniques for gene knockout and modification. The goal of this study was to evaluate two critical factors
Alberto Dessy et al.
Colloids and surfaces. B, Biointerfaces, 87(2), 236-242 (2011-06-17)
Therapeutic properties of Dead Sea Water (DSW) in the treatment of skin diseases such as atopic dermatitis, psoriasis and photo aging UV damaged skin have been well established. DSW is in fact rich in minerals such as calcium, magnesium, sodium
H-Y Chang et al.
Occupational and environmental medicine, 61(8), 697-702 (2004-07-20)
To evaluate the protective effectiveness of gloves from occupational exposure to 2-methoxyethanol (2-ME); and to examine the association of 2-methoxyacetic acid (MAA) in urine and plasma collected simultaneously from low 2-ME exposure and high 2-ME exposure workers in a semiconductor
Makoto Takei et al.
Toxicological sciences : an official journal of the Society of Toxicology, 118(2), 643-652 (2010-07-10)
Ethylene glycol monomethyl ether (EGME) is a widely used industrial solvent known to cause adverse effects to human and other mammals. Organs with high metabolism and rapid cell division, such as testes, are especially sensitive to its actions. In order

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