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213330

Sigma-Aldrich

Ammonium chloride

ACS reagent, ≥99.5%

Synonym(s):
Salmiac
Linear Formula:
NH4Cl
CAS Number:
Molecular Weight:
53.49
Beilstein:
4371014
EC Number:
MDL number:
eCl@ss:
38050207
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent

Quality Level

vapor density

1.9 (vs air)

vapor pressure

1 mmHg ( 160.4 °C)

Assay

≥99.5%

form

powder, crystals or chunks

impurities

≤0.005% insolubles

ign. residue

≤0.01%

pH

4.5-5.5 (25 °C, 5%)

mp

340 °C (subl.) (lit.)

anion traces

phosphate (PO43-): ≤2 ppm
sulfate (SO42-): ≤0.002%

cation traces

Ca: ≤0.001%
Fe: ≤2 ppm
Mg: ≤5 ppm
heavy metals: ≤5 ppm (by ICP)

SMILES string

N.Cl

InChI

1S/ClH.H3N/h1H;1H3

InChI key

NLXLAEXVIDQMFP-UHFFFAOYSA-N

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This Item
901230A45141029953
Ammonium chloride ACS reagent, ≥99.5%

Sigma-Aldrich

213330

Ammonium chloride

Ammonium chloride anhydrous, free-flowing, Redi-Dri™, ACS reagent, ≥99.5%

Sigma-Aldrich

901230

Ammonium chloride

Ammonium chloride ReagentPlus®, ≥99.5%

Sigma-Aldrich

A4514

Ammonium chloride

Ammonium chloride United States Pharmacopeia (USP) Reference Standard

USP

1029953

Ammonium chloride

vapor pressure

1 mmHg ( 160.4 °C)

vapor pressure

1 mmHg ( 160.4 °C)

vapor pressure

1 mmHg ( 160.4 °C)

vapor pressure

1 mmHg ( 160.4 °C)

assay

≥99.5%

assay

≥99.5%

assay

≥99.5%

assay

-

form

powder, crystals or chunks

form

powder or crystals

form

powder or crystals

form

-

impurities

≤0.005% insolubles

impurities

≤0.005% insolubles

impurities

-

impurities

-

pH

4.5-5.5 (25 °C, 5%)

pH

4.5-5.5 (25 °C, 5%)

pH

4.5-5.5 (20 °C, 50 g/L)

pH

-

General description

Crystals of ammonium chloride (NH4Cl) belong to the cubic crystal system. It can be synthesized by reacting HCl with aqueous ammonia solutions. NH4Cl is formed as a by-product during soda manufactured by Solvay process.

Application

Ammonium chloride (NH4Cl) has been used as one of the components of red blood cell (RBC) lysis buffer for use in various studies. It may be used as a catalyst in the preparation 3,4-dihydropyrimidin-2-(1H)-ones.
Inorganic ammonium ions (NH4+) effectively catalyze the aldol condensation of carbonyl compounds. It serves as a source of nitrogen during the preparation of trimethylamine hydrochloride (TMA·HCl).

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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CorpBase ID (for auto-filling citation data) null
Immune Cell Isolation from Mouse Femur Bone Marrow.
Liu X and Quan N.
Bio-protocol, 5(20) (2015)
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Selective Synthesis of Trimethylamine by Catalytic N-Methylation of Ammonia and Ammonium Chloride by utilizing Carbon Dioxide and Molecular Hydrogen.
Beydoun K, et al.
ChemCatChem, 8(1), 135-138 (2016)
Zeina S Khan et al.
Cellular and molecular bioengineering, 13(6), 591-604 (2020-12-08)
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