213330

Sigma-Aldrich

Ammonium chloride

ACS reagent, ≥99.5%

Synonym(s):
Salmiac
Linear Formula:
NH4Cl
CAS Number:
Molecular Weight:
53.49
Beilstein/REAXYS Number:
4371014
EC Number:
MDL number:
eCl@ss:
38050207
PubChem Substance ID:
NACRES:
NA.21

Quality Level

grade

ACS reagent

vapor density

1.9 (vs air)

vapor pressure

1 mmHg ( 160.4 °C)

assay

≥99.5%

form

powder, crystals or chunks

impurities

≤0.005% insolubles

ign. residue

≤0.01%

pH

4.5-5.5 (25 °C, 5%)

mp

340 °C (subl.) (lit.)

anion traces

phosphate (PO43-): ≤2 ppm
sulfate (SO42-): ≤0.002%

cation traces

Ca: ≤0.001%
Fe: ≤2 ppm
Mg: ≤5 ppm
heavy metals: ≤5 ppm (by ICP)

SMILES string

N.Cl

InChI

1S/ClH.H3N/h1H;1H3

InChI key

NLXLAEXVIDQMFP-UHFFFAOYSA-N

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General description

Crystals of ammonium chloride (NH4Cl) belong to the cubic crystal system. It can be synthesized by reacting HCl with aqueous ammonia solutions. NH4Cl is formed as a by-product during soda manufactured by Solvay process.

Application

Ammonium chloride (NH4Cl) has been used as one of the components of red blood cell (RBC) lysis buffer for use in various studies. It may be used as a catalyst in the preparation 3,4-dihydropyrimidin-2-(1H)-ones.
Inorganic ammonium ions (NH4+) effectively catalyze the aldol condensation of carbonyl compounds. It serves as a source of nitrogen during the preparation of trimethylamine hydrochloride (TMA·HCl).

Packaging

25, 500, 6×500 g in poly bottle
12, 25 kg in poly drum
2.5, 4×2.5 kg in poly bottle
50 kg in fiber drum

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

hazcat

Acute Tox. 4 Oral - Eye Irrit. 2

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Selective Synthesis of Trimethylamine by Catalytic N-Methylation of Ammonia and Ammonium Chloride by utilizing Carbon Dioxide and Molecular Hydrogen.
Beydoun K, et al.
ChemCatChem, 8(1), 135-138 (2016)
Mark E Kusek et al.
Journal of visualized experiments : JoVE, (83)(83), e50823-e50823 (2014-01-17)
Mucosal surfaces serve as protective barriers against pathogenic organisms. Innate immune responses are activated upon sensing pathogen leading to the infiltration of tissues with migrating inflammatory cells, primarily neutrophils. This process has the potential to be destructive to tissues if...
Immune Cell Isolation from Mouse Femur Bone Marrow.
Liu X and Quan N.
Bio-protocol, 5(20) (2015)
Romina Frare et al.
FEMS microbiology letters, 367(23) (2020-11-27)
Nitrogen is a most important nutrient resource for Escherichia coli and other bacteria that harbor the glnKamtB operon, a high-affinity ammonium uptake system highly interconnected with cellular metabolism. Although this system confers an advantage to bacteria when growing under nitrogen-limiting...
514502
CorpBase ID (for auto-filling citation data) null

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