Calcium chloride dihydrate

ACS reagent, ≥99%

Empirical Formula (Hill Notation):
CaCl2 · 2H2O
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


ACS reagent

vapor pressure

0.01 mmHg ( 20 °C)


99.0-105.0% (ACS specification)


powder or crystals


≤0.003% oxidizers
≤0.01% NH4OH pptd.
≤0.01% calcium chloride
≤0.01% insolubles


4.5-8.5 (25 °C, 5%)


176 °C (dec.) (lit.)

anion traces

sulfate (SO42-): ≤0.01%

cation traces

Ba: ≤0.005%
Fe: ≤0.001%
K: ≤0.01%
Mg: ≤0.005%
NH4+: ≤0.005%
Na: ≤0.02%
Sr: ≤0.1%
heavy metals: ≤5 ppm (by ICP)

SMILES string




InChI key


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General description

Calcium chloride dihydrate is a moisture resistant, cheap and commonly available calcium salt. Its efficacy as a chiral catalyst for various asymmetric organic reactions has been evaluated.


Calcium chloride dihydrate may be used in combination with sodium borohydride for the asymmetric reduction of 1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-[(1S)-2-hydroxy-1-phenylethylamino]ethanone to form (1R)-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-2-[(1S)-2-hydroxy-1-phenylethylamino]ethanol.
Calcium chloride dihydrate has been used as a calcium supplement for the DMEM (Dulbecco′s modified Eagle′s medium) for use in cell culture studies. It has also been used to prepare the synthetic brine solution.
It may be used in the preparation of calcium-alginate beads.


25, 500, 6×500 g in poly bottle
2.5 kg in poly bottle
12 kg in fiber drum


Exclamation mark

Signal Word


Hazard Statements


Eye Irrit. 2


13 - Non Combustible Solids

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Calcium Chloride (CaCl2) as Catalyst for Asymmetric Organic Reactions.
Tsubogo T, et al.
Topics in Catalysis, 10(13), 935-939 (2014)
Emad Tolba et al.
Molecules (Basel, Switzerland), 25(10) (2020-05-23)
There is a strong interest in cement additives that are able to prevent or mitigate the adverse effects of cracks in concrete that cause corrosion of the reinforcement. Inorganic polyphosphate (polyP), a natural polymer that is synthesized by bacteria, even...
A mild, enantioselective synthesis of (R)-salmeterol via sodium borohydride-calcium chloride asymmetric reduction of a phenacyl phenylglycinol derivative
Bream RN, et al.
Journal of the Chemical Society. Perkin Transactions 1, 20, 2237-2242 (2002)
Leyu Cui et al.
Analytical chemistry, 86(22), 11055-11061 (2014-11-05)
The methylene blue (MB) two-phase titration method is a rapid and efficient method for determining the concentrations of anionic surfactants. The point at which the aqueous and chloroform phases appear equally blue is called Epton's end point. However, many inorganic...
George Pasparakis et al.
International journal of pharmaceutics, 323(1-2), 34-42 (2006-07-11)
The aim of the present work was to investigate the swelling behavior and the in vitro release of the antihypertensive drug verapamil hydrochloride from calcium alginate and chitosan treated calcium alginate beads. Calcium-alginate beads, chitosan-coated alginate beads and alginate-chitosan mixed...

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