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243973

Sigma-Aldrich

Sodium bisulfite

ACS reagent

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Synonym(s):
Sodium hydrogensulfite
Empirical Formula (Hill Notation):
NaHSO3
CAS Number:
Molecular Weight:
104.06
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent

Quality Level

form

powder or crystals

concentration

≥58.5% SO2

impurities

≤0.005% insolubles

pH

4.3 (10 g/L)

anion traces

chloride (Cl-): ≤0.02%

cation traces

Fe: ≤0.002%
heavy metals (as Pb): ≤0.001%

SMILES string

[Na+].OS([O-])=O

InChI

1S/Na.H2O3S/c;1-4(2)3/h;(H2,1,2,3)/q+1;/p-2

InChI key

DWAQJAXMDSEUJJ-UHFFFAOYSA-L

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This Item
13438PHR1434799394
Sodium bisulfite ACS reagent

Sigma-Aldrich

243973

Sodium bisulfite

Essential Grade
Sodium Metabisulfite Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1434

Sodium Metabisulfite

-
Sodium bisulfite anhydrous, free-flowing, Redi-Dri™, ACS reagent

Sigma-Aldrich

799394

Sodium bisulfite

-
form

powder or crystals

form

liquid

form

-

form

powder

impurities

≤0.005% insolubles

impurities

-

impurities

-

impurities

≤0.005% insolubles

pH

4.3 (10 g/L)

pH

-

pH

-

pH

4.3 (10 g/L)

anion traces

chloride (Cl-): ≤0.02%

anion traces

-

anion traces

-

anion traces

chloride (Cl-): ≤0.02%

cation traces

Fe: ≤0.002%, heavy metals (as Pb): ≤0.001%

cation traces

-

cation traces

-

cation traces

Fe: ≤0.002%, heavy metals (as Pb): ≤0.001%

General description

Sodium bisulfite is a widely used industrial chemical as a reducing agent, catalyst, and preservative in pharmaceuticals and foods due to its antioxidative and antibacterial effects.
The aqueous solutions of sodium bisulfite are acidic in nature. Degradation of sodium bisulfite with acid forms sulfur dioxide gas.

Application

Sodium bisulfite (NaHSO3) has been used as a reagent to compose the immunoprecipitation (IP) buffer to chemically modify DNA and to synthesize arsenolipids (AsL).
It can also be used as a reagent during the synthesis of 5,6-dihydrouracil-6-sulfonate.
Sodium bisulfite can be used as:
  • A reagent to synthesize aldehyde-bisulfite adducts from aromatic and aliphatic aldehydes.
  • A catalyst in the solvent-free etherification of aromatic/aliphatic alcohols to synthesize symmetric and unsymmetric ethers via intermolecular dehydration.
  • An additive in the copper-catalyzed homocoupling of ketoxime carboxylates to synthesize symmetrical pyrroles.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Supplementary Hazards

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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