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270458

Sigma-Aldrich

1-Methyl-2-pyrrolidinone

suitable for HPLC, ≥99%

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Synonym(s):
1-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidone, NMP
Empirical Formula (Hill Notation):
C5H9NO
CAS Number:
Molecular Weight:
99.13
Beilstein/REAXYS Number:
106420
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

vapor density

3.4 (vs air)

Quality Level

vapor pressure

0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

assay

≥99%

form

liquid

autoignition temp.

518 °F

purified by

glass distillation

expl. lim.

9.5 %

technique(s)

HPLC: suitable

impurities

<0.050% water

color

APHA: ≤10

refractive index

n20/D 1.47 (lit.)

pH

7.7-10.0 (20 °C, 100 g/L)

bp

202 °C (lit.)
81-82 °C/10 mmHg (lit.)

mp

−24 °C (lit.)

density

1.028 g/mL at 25 °C (lit.)

λ

H2O reference

UV absorption

λ: 285 nm Amax: 1.00
λ: 300 nm Amax: 0.50
λ: 325 nm Amax: 0.10
λ: 350-400 nm Amax: 0.01

application(s)

food and beverages

SMILES string

CN1CCCC1=O

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

InChI key

SECXISVLQFMRJM-UHFFFAOYSA-N

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1 of 4

This Item
78769494496443778
1-Methyl-2-pyrrolidinone suitable for HPLC, &#8805;99%

270458

1-Methyl-2-pyrrolidinone

-
1-Methyl-2-pyrrolidinone analytical standard

78769

1-Methyl-2-pyrrolidinone

-
1-Methyl-2-pyrrolidinone biotech. grade, &#8805;99.7%

494496

1-Methyl-2-pyrrolidinone

-
1-Methyl-2-pyrrolidinone ACS reagent, &#8805;99.0%

443778

1-Methyl-2-pyrrolidinone

Essential Grade
assay

≥99%

assay

≥99.9% (GC)

assay

≥99.7%

assay

≥99.0%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

form

liquid

form

-

form

liquid

form

liquid

vapor pressure

0.29 mmHg ( 20 °C), 0.99 mmHg ( 40 °C)

vapor pressure

0.29 mmHg ( 20 °C), 0.99 mmHg ( 40 °C)

vapor pressure

0.29 mmHg ( 20 °C), 0.99 mmHg ( 40 °C)

vapor pressure

0.29 mmHg ( 20 °C), 0.99 mmHg ( 40 °C)

General description

1-Methyl-2-pyrrolidinone, a tertiary amide, is widely employed as an organic solvent. It participates in the sonochemical synthesis of high quality MOF(Metal-Organic Framework)-177 crystals.
It also participates in the following:
  • synthesis of cyanotrimethylsilane
  • decarbonylation of aldehydes
  • reduction of benzaldehydes and ketones to the corresponding alcohols
  • preparation of natural products

Application

1-Methyl-2-pyrrolidinone (NMP) has been used as a solvent to study the dispersion ability of acrylate polymers for graphene. It has also been used for the fabrication of working electrodes for electrochemical measurements in a study.

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pictograms

Exclamation markHealth hazard

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 1

flash_point_f

195.8 °F - Pensky-Martens closed cup

flash_point_c

91 °C - Pensky-Martens closed cup


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High quality MOF-177 crystals in the size range of 5-20 microm were successfully synthesized via a sonochemical route in a substantially reduced synthesis time (40 min) in the presence of low-cost NMP (1-methyl-2-pyrrolidone) as a solvent. Microwave heating in NMP
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