270458

1-Methyl-2-pyrrolidinone

suitable for HPLC, ≥99%

• Synonym(s): 1-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidone, NMP
• Empirical Formula (Hill Notation): C₅H₉NO
• CAS Number: 872-50-4
• Molecular Weight: 99.13
• Beilstein: 106420
• EC Number: 212-828-1
• MDL number: MFCD00003193
• PubChem Substance ID: 329752940
• NACRES: NA.21

Properties

• vapor density: 3.4 (vs air)
• Quality Level: 100
• vapor pressure: 0.29 mmHg ( 20 °C); 0.99 mmHg ( 40 °C)
• Assay: ≥99%
• form: liquid
• autoignition temp.: 518 °F
• purified by: glass distillation
• expl. lim.: 9.5 %
• technique(s): HPLC: suitable
• impurities: <0.050% water
• color: APHA: ≤10
• refractive index: n20/D 1.47 (lit.)
• pH: 7.7-10.0 (20 °C, 100 g/L)
• bp: 202 °C (lit.); 81-82 °C/10 mmHg (lit.)
• mp: −24 °C (lit.)
• density: 1.028 g/mL at 25 °C (lit.)
• λ: H₂O reference
• UV absorption: λ: 285 nm A_max: 1.00; λ: 300 nm A_max: 0.50; λ: 325 nm A_max: 0.10; λ: 350-400 nm A_max: 0.01
• application(s): food and beverages
• SMILES string: CN1CCCC1=O
• InChI: 1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
• InChI key: SECXISVLQFMRJM-UHFFFAOYSA-N

Description

General description

1-Methyl-2-pyrrolidinone, a tertiary amide, is widely employed as an organic solvent. It participates in the sonochemical synthesis of high quality MOF(Metal-Organic Framework)-177 crystals.
It also participates in the following:

• synthesis of cyanotrimethylsilane
• decarbonylation of aldehydes
• reduction of benzaldehydes and ketones to the corresponding alcohols
• preparation of natural products

Application

1-Methyl-2-pyrrolidinone (NMP) has been used as a solvent to study the dispersion ability of acrylate polymers for graphene. It has also been used for the fabrication of working electrodes for electrochemical measurements in a study.

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Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H315 - H319 - H335 - H360D
• Precautionary Statements: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 1
• Flash Point(F): 195.8 °F - Pensky-Martens closed cup
• Flash Point(C): 91 °C - Pensky-Martens closed cup